蜂针疗法治疗膝骨性关节炎的Meta分析

A Meta-analysis of Bee-sting Acupuncture in the Treatment of Knee Osteoarthritis

目的系统评价蜂针疗法对膝骨性关节炎(KOA)患者的干预效果。方法计算机全面检索公开发表在国内外期刊上关于蜂针疗法治疗KOA患者的随机对照试验(RCTs)。使用Rev Man5.3软件进行Meta分析,采用Cochrane Handbook5.0标准进行质量评估。结果最终纳入7篇文献总计481例患者。Meta分析结果表明:蜂针疗法与常规西药、普通针灸、中频电疗法相比有效率较好(P<0.05);蜂针疗法+内服中药与内服中药有效率对比无明显差异(P>0.05);蜂针疗法总体疗效优于其他疗法(OR=3.68,95%CI[2.26,5.98])。结论蜂针疗法治疗膝骨性关节炎(KOA)患者症状改善效果明显,但需更高质量的临床研究支持其临床疗效。

Objective To evaluate the intervention effect of bee-sting acupuncture therapy in patients with knee osteoarthritis（KOA）.Methods A computer-based search of a comprehensive search of published randomized controlled trials（RCTs） published in domestic and foreign journals on bee acupuncture in patients with KOA. Rev Man5. 3 software was used for Meta-analysis,and quality evaluation was carried out by using Cochrane Handbook5. 0 standard. Results A total of 7 articles were included,with a total of 581 patients. Metaanalysis showed that： Bee-sting therapy was more effective than conventional Western medicine,general acupuncture and mid-frequency electrotherapy（P〈0. 05）. There was no significant difference in the effective rate of bee-sting acupuncture and oral administration of traditional Chinese medicine versus oral administration of traditional Chinese medicine（P〈0. 05）. The overall efficacy of bee-sting acupuncture therapy is superior to other therapies（OR = 3. 68,95% CI [2. 26,5. 98]）. Conclusion The bee-sting acupuncture therapy in patients with KOA is effective in improving the prognosis,but higher quality clinical research is needed to support its clinical effect.