摘要
目的观察应用肺胃相关理论组方的金水六君煎合补中益气汤加减治疗咳嗽变异性哮喘的临床疗效及安全性。方法选取符合纳入标准的咳嗽变异性哮喘患者110例,随机分为治疗组55例和对照组55例。对照组在呼吸内科常规护理的基础上给予吸入用布地耐德混悬液联合孟鲁司特咀嚼片治疗;治疗组在呼吸内科常规护理的基础上给予口服中草药(金水六君煎合补中益气汤加减),均治疗8周后观察两组患者治疗前后症候积分、肺功能,统计临床疗效。结果治疗后治疗组临床疗效总有效率为94.55%,对照组临床疗效总有效率为81.82%,两组比较差异有统计学意义(P<0.05)。治疗后两组患者症候积分、肺功能情况与治疗前比较,差异有统计学意义(P<0.05);且治疗后治疗组症候积分、肺功能与对照组比较,差异有统计学意义(P<0.05)。结论应用肺胃相关理论组方的金水六君煎合补中益气汤加减有效地缓解咳嗽变异性哮喘患者的临床症状,改善肺功能;为临床探索中医药治疗咳嗽变异性哮喘提供了有效的方剂,值得进一步推广及应用。
Objective To observe the clinical therapeutic effects and safety analysis on cough variant asthma treated with modified jinshui liujun jian and buzhong yiqi tang on the base of lung and stomach theories in TCM. Methods A total of 110 patients of cough variant asthma,in compliance with the inclusive criteria were collected and randomized into a treatment group( 55 cases) and a control group( 55 cases). In the control group,besides the usual nursing care in the department of respiratory internal medicine,the inhalation of budesonide suspension and montelukast chewable tablets were prescribed in combination. In the treatment group,besides the usual nursing care,the herbal decoction was given for oral administration( the modified jinshui liujun jian and buzhong yiqi tang). In 8 weeks of treatment,the symptom score and lung function were observed before and after treatment in the two groups and the clinical therapeutic effects were analyzed statistically. Results The total effective rate was 94. 55% in the treatment group and was 81. 82% in the control group after treatment,indicating the significant difference( P〈0. 05). After treatment,the differences in the symptom score and lung function were significant between the two groups( P〈0. 05). And the results in the treatment group were different significantly as compared with the control group( P〈0. 05). Conclusion The modified jinshui liujun jian and buzhong yiqi tang on the base of lung and stomach theories in TCM relieve the clinical symptoms and improve lung function in the patients of cough variant asthma. This therapy provides the effective formula for the treatment of the disease with TCM and deserves to be further promoted in clinical application.
作者
张妍
张磊
李艳
朱晓婷
刘霞
潘玲玲
ZHANG Yan;ZHANG Lei;LI Yan;ZHU Xiao - ting;LIU Xia;PAN Ling - ling(Tangsban Fengrun District People's Hospital, Tangshan Hebei 064000;Tangshan Chinese Medicine Hospital,Tangshan Hebei 063000;Tangshan People's Hospital, Tangshan Hebei 063001;Hospital of Tangshan Iron and Steel Co. Ltd. ,Tangshan Hebei 063020)
出处
《世界中西医结合杂志》
2018年第3期374-376,380,共4页
World Journal of Integrated Traditional and Western Medicine
基金
2016年度河北省中医药管理局科学技术课题(2016115)
关键词
咳嗽变异性哮喘
补中益气汤
金水六君煎
肺胃相关
Cough Variant Asthma
Buzhong Yiqi Tang
Jinshui Liujun Jian
Relevant with Lung and Stomach