番茄红素制剂化技术研究进展

Research progress of lycopene preparation technology

番茄红素抗氧化活性强,具有延缓衰老、抗动脉粥样硬化、防癌、抗癌、预防心血管疾病等效果。但番茄红素稳定性差、脂溶性的特点导致其生物利用度低,限制了其应用领域。因此,通过制剂化处理提高番茄红素的稳定性、水溶性、生物利用度具有重要价值。综述了番茄红素制剂化技术,主要包括微胶囊化技术、脂质体技术、纳米分散体技术、包埋技术、乳化技术和超临界流体技术。

Lycopene has a positive effect on delaying senility,anti-atherosclerosis,cancer prevention and anti-cancer,and prevention of cardiovascular diseases due to its strong antioxidant activity. But it has some disadvantages,such as lack of stability,low bioavailability caused by the property of fat-solubility,which limit the application. Therefore,it is of great value to improve the stability,water solubility and bioavailability of lycopene after being treated by preparation process. The preparation technology of lycopene,including microencapsulation technology,liposome technology,nano dispersion technology,embedding technology,emulsification technology and supercritical fluid technology,are reviewed.