β-磷酸三钙人工骨联合rhBMP-2重建肱骨近端良性骨肿瘤及骨瘤样病变刮除

β-tricalcium phosphate artificial bone combined with rhBMP-2 is helpful for the reconstruction of proximal humerus benign bone tumor and osteoid lesion after curettage

目的:探讨β-磷酸三钙(β-TCP)人工骨联合重组人骨形态发生蛋白-2(rhBMP-2)填充修复肱骨近端良性骨瘤样病变刮除后骨缺损效果。方法:采用β-TCP人工骨联合rhBMP-2填充法治疗肱骨近端良性肿瘤样病变13例,观察植骨后的愈合情况。结果:所有病例均达到植骨愈合,仅有2例术后出现手术切口延期愈合,均未出现植骨部位骨折及肿瘤复发等并发症。结论:β-TCP人工骨联合rhBMP-2能较好对肱骨近端良胜骨肿瘤刮除后骨缺损的重建,骨愈合效果良好。

Objective： To investigate the effect of β-tricalcium phosphate（ β-TCP） artificial bone combined with recombinant human bone morphogenetic protein-2（ rhBMP-2） filling in the repair of bone defect after benign osteoma like osteoma of the proximal humerus. Methods： 13 cases of benign tumor like lesions near the proximal humerus were treated with β-TCP artificial bone and rhBMP-2 filling method.The healing of bone graft was observed. Results： All cases achieved bone graft healing. Only 2 cases had delayed healing after operation. There were no complications such as bone graft fracture and tumor recurrence. Conclusion： The combination of β-TCP artificial bone and rhBMP-2 can better reconstruct the bone defect after curettage of the proximal humeral bone tumor,and the bone healing effect is good.