药物涂层球囊在冠状动脉回旋支开口病变介入治疗中的临床应用

Application of drug-coated balloon in interventional treatment of the ostium lesions of LCX

目的探讨药物涂层球囊应用于冠状动脉回旋支开口病变的可行性。方法选择2015年10月至2017年6月在首都医科大学附属北京朝阳医院心脏中心经冠状动脉造影证实冠状动脉回旋支开口病变的患者12例,Medina分型0,0,1;行经皮冠状动脉介入术(PCI),应用药物涂层球囊处理病变,术后即刻行冠状动脉造影检查。术后6个月临床随访和复查冠状动脉造影,统计患者主要不良心血管事件。结果 12例患者PCI成功率为100%,血管最小管腔直径由术前的(0.31±0.12)mm增加至术后的(2.86±0.43)mm(P<0.001)。术后6个月内患者未发生主要不良心血管事件;10例患者复查冠状动脉造影,造影随访率83.3%,造影随访无再狭窄,管腔直径(2.93±0.39)mm。结论药物涂层球囊应用于冠状动脉回旋支开口病变安全、有效。

Objective To study the application of drug-coated balloon in treating the ostium lesions of LCX during percutaneous coronary intervention. Methods The 12 patients with the ostium lesions of LCX admitted to our hospital from October 2015 to July 2017 were included in this study. We use drug-coated balloon（DCB） to treat the LCX lesions during PCI,the patients underwent coronary angiography immediately after surgery and were followed up after 6 months of operation. 10 patients（83. 3%） underwent coronary angiography 6 months later. The MACE were recorded. Results The success rate of PCI was 100%. No complication occured during and after operation. There were no MACE events in the follow up,The minimal lumen diameters of the LCX increased from（0. 31 ± 0. 12） mm before operation to（2. 86 ± 0. 43） mm after operation（P〈0. 001）. No MACE occurred in 6 months after operation; the coronary angiography 6 months later show there were no coronary restenosis in all cases. The diameters of the LCX were（2. 93 ± 0. 39） mm.Conclusions Drug-coated balloon is safe and effective in treating the ostium lesions of LCX during PCI.