摘要
慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)属"本虚标实"之证,气虚为"本",痰饮、瘀血为"标",气道重构是COPD的病理关键,而血管内皮生长因子(vascular endothelial growth factor,VEGF)是COPD气道重构发生、发展的重要因素,通过就益气化痰祛瘀法对COPD气道重构及VEGF影响的研究进行论述,为COPD的防治提供新的治疗思路。
Chronic obstructive pulmonary disease(COPD) is the evidence of" virtual obstructive pulmonary disease",Qi deficiency is" essence", phlegm and blood stasis are" standard", and airway remodeling is the key factor of COPD, while vascular endothelial growth factor(VEGF) is an important factor in the development and progression of airway remodeling in COPD. This article discusses the research on the effects of Qi-supplementing, resolving phlegm and blood stasis therapy on the airway remodeling and VEGF in COPD, and provides a new therapeutic approach for the prevention and treatment of COPD.
作者
程建超
李泽庚
张星星
童佳兵
杨勤军
倪萍
CHENG Jianchao;L;ZHANG Xingxing;TONG Jiabing;D YANG Qingjun;DNI Ping(Anhui University of Chinese Medicine,Anhui Hefei 230038,China;Anhui Provincial Hospital of Traditional Chinese Medicine,Anhui Hefei 230031,China)
出处
《中医药临床杂志》
2018年第6期987-990,共4页
Clinical Journal of Traditional Chinese Medicine
基金
安徽省自然科学基金(No:1708085MH197)
国家中医药管理局肺气虚证重点研究室(国中药函[2009]95号)
中医科学院自主选题项目(No:编号:2010LC-027A)
国家自然科学基金(NO:81373598)
关键词
慢性阻塞性肺疾病
气道重构
血管内皮生长因子
益气化痰祛瘀法
Chronic obstructive pulmonary disease
Airway remodeling
Vascular endothelial growth factor
YiqiHuatan Quyu method