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Effects of Ginsenoside Rb1 Babu Agent on the Amplitude of Microvascular Vasomotion

Effects of Ginsenoside Rb1 Babu Agent on the Amplitude of Microvascular Vasomotion
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摘要 [Objectives] To study the effects of ginsenoside Rbl Babu agent on the amplitude of microvascular vasomotion. [Methods]The in vitro transdermal permeation of ginsenoside Rbl Babu agent was performed by using intelligent transdermal apparatus,and the percutaneous fluid was collected and analyzed by using high performance liquid chromatography( HPLC). The Babu agent was stuck on the skin of acupoint area,determined by Laser Doppler Flowmeter,and amplitude of microvascular vasomotion of acupoint area was recorded. [Results] With the extension of transdermal time,the cumulative permeation rate of ginsenoside Rbl increased. The amplitude of microvascular vasomotion could be significantly increased with the application of ginsenoside Rbl Babu agent( P < 0. 01). [Conclusions]The drug delivery system of ginsenoside Rbl Babu agent can release the drug into the acupoint,increase the amplitude of microvascular vasomotion,and achieve the effect of acupuncture. Therefore,ginsenoside Rbl Babu agent can replace the acupuncture clinically to treat diseases. [Objectives] To study the effects of ginsenoside Rbl Babu agent on the amplitude of microvascular vasomotion. [Methods]The in vitro transdermal permeation of ginsenoside Rbl Babu agent was performed by using intelligent transdermal apparatus,and the percutaneous fluid was collected and analyzed by using high performance liquid chromatography( HPLC). The Babu agent was stuck on the skin of acupoint area,determined by Laser Doppler Flowmeter,and amplitude of microvascular vasomotion of acupoint area was recorded. [Results] With the extension of transdermal time,the cumulative permeation rate of ginsenoside Rbl increased. The amplitude of microvascular vasomotion could be significantly increased with the application of ginsenoside Rbl Babu agent( P 〈 0. 01). [Conclusions]The drug delivery system of ginsenoside Rbl Babu agent can release the drug into the acupoint,increase the amplitude of microvascular vasomotion,and achieve the effect of acupuncture. Therefore,ginsenoside Rbl Babu agent can replace the acupuncture clinically to treat diseases
出处 《Medicinal Plant》 CAS 2018年第2期78-82,共5页 药用植物:英文版
基金 Supported by Fundamental Study on Rules and Influencing Factors of Specificity of Acupoint Effect(2012CB518502)
关键词 Ginsenoside Rbl Babu agent Microvessel VASOMOTION AMPLITUDE Ginsenoside Rbl Babu agent Microvessel Vasomofion Amplitude
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