摘要
循环肿瘤细胞(circulating tumor cell,CTC)检测是一种新型的"液体活检"技术,具有无创、便捷、实时、整体、精准和可重复操作等特点,为临床提供了从肿瘤细胞到分子水平的分析平台,弥补了现有临床肿瘤诊断方法的不足,有助于实现肿瘤患者的精准医疗。本文主要就CTC检测技术的临床应用价值和常用方法等最新进展作一综述。
The detection of circulating tumor cells is a new type of " liquid biopsy" technique. It has the advantages of non-invasiveness,convenience,real-time,integrity,precision and repeatability.The technique provides a clinical analysis platform from cellular to molecular levels,and makes up the deficiency of the existing methods of cancer diagnosis,to facilitate more accurate medical treatment for cancer patients. This article reviews the latest progress on the clinical application and common methods of circulating tumor cell detection.
作者
黄子凌
宇小婷
易祥华
HUANG Zi-ling;YU Xiao-ting;YI Xiang-hua(Dept.of Pathology,Tongji Hospital,Tongji University,Shanghai 200065,China)
出处
《同济大学学报(医学版)》
CAS
2018年第3期123-127,共5页
Journal of Tongji University(Medical Science)
基金
国家自然科学基金(81600043
81401882)
上海市科学技术委员会医学重点科技攻关专项基金(09411951600)
上海市卫生局医学重点专项基金(20134034)
关键词
循环肿瘤细胞
病理技术
精准医学
circulating tumor cells
pathological technique
precision medicine