移动应用程序干预对改善院外癌症患者生活质量的Meta分析

Effect of APP Intervention on Quality of Life among Out-patient with Cancer:A Meta-analysis

目的探讨移动应用程序(mobile application,APP)干预对院外癌症患者生活质量的影响。方法计算机检索Cochrane Library、Pubmed、CINHAL、荷兰医学文摘数据库(the excerpta medica excerptamedica database,Embase)、中国生物医学文献数据库(Chinese Biology Medicine disc,CBMdisc)、中国期刊全文数据库(Chinese national knowledge infrastructure,CNKI)、万方数据库和维普期刊资源整合平台等数据库中关于APP干预对院外癌症患者生活质量影响的随机对照试验(randomized controlled trial,RCT)和类实验研究(controlled clinical trail,CCT),检索时限为建库至2017年12月。由2名研究员按照纳入和排除标准筛选文献、提取资料、评价质量,然后采用RevMan 5.3软件进行Meta分析。结果共纳入7项研究,1568例患者。Meta分析结果提示,APP干预对改善癌症患者的整体生活质量、躯体功能、角色功能、情绪功能、认知功能、社会功能、疲乏症状、疼痛症状、气促、便秘、腹泻有显著效果(P<0.05),对改善恶心呕吐症状、失眠、食欲丧失、经济困难无显著效果(P>0.05)。结论与常规方式相比较,基于APP的干预措施对改善癌症患者的整体生活质量、部分功能领域和症状领域的质量均有显著效果。

Objective To evaluate the effect of APP intervention on quality of life among out patient with Cancer. Methods The Cochrane I.ibrary,Pubmed,Embase,CINHAI.,Chinese biomedical literature data base,CNKI,Wang Fang and VIP database were searched for the randomized controlled trial and controlled clinical trail of the APP intervention on quality of life among out patient with cancer from inception to De cember 2017. The quality of studies was critically appraised and data were extracted by two reviewers inde pendently. The RevMan 5.3 software was used for the meta analysis. Results Totally 7 studies and 1568 patients were included. Meta analysis showed that APP intervention can effectively improve the overall quality of life, physical function, role function, emotional function, cognitive function, social function, fa tigue,pain,shortness of breath,constipation and diarrhea of cancer patients （P〈0.05）. APP intervention can＇t significantly improve nausea, vomiting, insomnia, loss of appetite and economic difficulties of cancer patients （P〉0. 05）. Conclusions Compared with conventional methods,APP intervention has significant effects on improving the overall quality of life,some functions and symptoms of cancer patients.