腹腔镜结直肠癌根治术治疗结直肠癌患者的疗效及对胃肠功能的影响

Clinical wfficacy of laparoscopic radical resection for colorectal cancer and its effect on gastrointestinal function

目的探讨腹腔镜下结直肠癌根治术治疗结直肠癌患者的临床疗效和对患者胃肠功能的影响。方法选取2016年1月至2018年1月间安康市石泉县中医医院收治的接受结直肠癌根治术的91例结直肠癌患者进行回顾性分析,将接受腹腔镜结直肠癌根治术治疗的46例结直肠癌患者纳入观察组,接受传统开腹手术治疗的45例结直肠癌患者纳入对照组,比较两组患者手术及治疗情况、术后胃肠功能恢复情况和并发症发生情况。结果观察组患者的手术持续时间、术中出血量及总住院时间均低于对照组患者,差异均有统计学意义(均P<0.05)。两组患者术中切除标本长度和淋巴结清扫数量比较,差异无统计学意义(P>0.05)。观察组患者肛门排气时间、肠鸣音恢复时间和开始进食时间均低于对照组患者,差异均有统计学意义(均P<0.05)。观察组患者胃动素和胃泌素分泌水平高于对照组患者,差异均有统计学意义(均P<0.05)。观察组患者并发症发生率为17.4%,低于对照组患者的40.0%,差异有统计学意义(P<0.05)。结论与传统开腹手术相比,腹腔镜结直肠癌根治术临床疗效显著,手术术后恢复较好,可促进患者术后胃肠功能的恢复,且术后并发症较少,适宜临床推广。

Objective To investigate the clinical efficacy of laparoscopic radical resection for colorectal cancer and the effect on gastrointestinal function. METHODS A total of 91 patients with colorectal cancer undergoing radical resection treated at Traditional Chinese Medicine Hospital of Shiquan County from January 2016 to January 2018 were selected as the study subjects,and were retrospectively analyzed. Fortysix patients who underwent laparoscopic radical resection for colorectal cancer were included in the observation group and 45 patients who underwent conventional laparotomy were included in the control group. The operation and treatment status,postoperative recovery of gastrointestinal function,and complications were compared between the two groups. Results The duration of surgery,the amount of bleeding,and the total length of hospital stay were less in the observation group than in the control group（ P〈0. 05）. There was no significant difference in the length of specimen resected and number of lymph nodes removed between the groups（ P〉0. 05）. The anus exhaust time,bowel sound recovery time,and start of eating time were shorter in the observation group than in the control group（ all P〈0. 05）. The motilin and gastrin levels were significantly higher in the observation group than in the control group（ all P〈0. 05）. The incidence of complications was 17. 4% in the observation group which was lower than 40. 0% of the control group（ P〈0. 05）. Conclusion Compared with traditional laparotomy surgery,laparoscopic radical resection for colorectal cancer has a significant clinical efficacy,and the surgical condition is optimized,which promotes the recovery of postoperative gastrointestinal function with few complications. It is suitable for clinical promotion.