摘要
本文采用消痔灵注射液成功地创建了大鼠前列腺纤维增生性炎症病理模型,观察中药前列腺汤对其影响。光学显微镜显示:给药组大鼠前列腺间质炎细胞浸润及纤维母细胞增生程度均轻于给水组。透射电镜结果表明:给药组的腺细胞表面分泌颗粒及腺腔内金属颗粒样物质(包括 Zn)均明显增加,胞浆内溶酶体增多。实验从细胞和亚细胞水平的结构变化为前列腺汤减轻炎症反应和纤维组织增生提供了客观依据。
Herbal prostatitis decoction is a great effective prescription to treat chronic prostatitis in promoting the blood circulation and relieving the stasis.The authors had succeeded in making rats experimental fibrous proliferation type prostatitis models by using Xiaozhiling(消痔灵)injection method.Rats were divided into two groups:the decoction-given group(DG) and the water-given group (WG).Microscopically, both inflammatory cell infiltration and fibroblast proliferation of interstitial tissue in the DG were slight than the WG(P<0.025,P<0.05).Transmission electron microscopic observations showed both the secretary particles and metal-granule-like substances (including Zn)of the gland cells in the DG were obviously increased.The lysosomes in the cytoplasm. were increased also.The results performed a certain experimental basis for the functional mecha- nism of the herbal prostatitis decoction treatment.
关键词
前列腺汤
实验性
前列腺炎
herbal
prostatitis decoction
experimental prostatitis
