摘要
Purpose To evaluate histopathologic signs of conjunctival in flammation in patients with conju nctival hyperemia induced by bimatoprost treatment.D esign Prospective interventional study.Methods The s tudy included 15eyes of 15patients scheduled for cataract surgery.Pa-tients in the treatment group(n=9)exhibited trace to moderate conjunctival hyperemia when treated with bi-matoprost 0.03%every day for 15to 30days before surgery.The control group(n=6)included untreated patients with no ocular disease other than cataract.Conjunctival biopsies were obtained for histologic evalu-ation with light microscopy.Result s Vascular congestion was observed in biopsies from 7patie nts(78%)in the bimatoprost group and 5patients(83%)in the control group.Signs of inflammation were fo und in biopsies from2patients(22%)in the bimatoprost group and 2pa-tients(33%)in the control group.Conclusions Histopathologic signs of inflammation were no more fre-quent in conjunctival specimens from bimatoprost-treated patients with trace to moderate hyperemia than in those from untreated control subjects.
Purpose To evaluate histopathologic signs of conjunctival in flammation in patients with conju nctival hyperemia induced by bimatoprost treatment.D esign Prospective interventional study.Methods The s tudy included 15eyes of 15patients scheduled for cataract surgery.Pa-tients in the treatment group(n=9)exhibited trace to moderate conjunctival hyperemia when treated with bi-matoprost 0.03%every day for 15to 30days before surgery.The control group(n=6)included untreated patients with no ocular disease other than cataract.Conjunctival biopsies were obtained for histologic evalu-ation with light microscopy.Result s Vascular congestion was observed in biopsies from 7patie nts(78%)in the bimatoprost group and 5patients(83%)in the control group.Signs of inflammation were fo und in biopsies from2patients(22%)in the bimatoprost group and 2pa-tients(33%)in the control group.Conclusions Histopathologic signs of inflammation were no more fre-quent in conjunctival specimens from bimatoprost-treated patients with trace to moderate hyperemia than in those from untreated control subjects.
出处
《世界核心医学期刊文摘（眼科学分册）》
2005年第1期21-22,共2页
Digest of the World Core Medical Journals:Ophthalmology
