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缬沙坦治疗慢性心力衰竭的疗效 被引量:5

THE CLINICAL EFFICACY OF VALSARTAN FOR TREATMENT OF CHRONIC CONGESTIVE HEART FAILURE
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摘要 目的 :评价缬沙坦对慢性心力衰竭的疗效。方法 :经基础治疗 ,心功能仍为NYHA 3~ 4级患者 6 0例 ,随机分成 2组 ,即合用组 (n =30 )及对照组 1(n =30 ) ,合用组加用缬沙坦治疗 ,对照组继续原治疗。另外不能耐受ACEI者 6 0例 ,2周后 ,分为二组 ,即单用组 (n =30 )及对照组 2 (n =30 ) ,单用组接受缬沙坦治疗 ,对照组继续停用ACEI治疗。合用组及单用组均每天接受 80~ 16 0mg缬沙坦治疗。结果 :合用或单用缬沙坦均能改善心功能 ,提高EF ,缩小左室舒张期内径。结论 :缬沙坦可以单用或与ACEI联合应用治疗心力衰竭 ,是不能耐受ACEI者的代替药物。 Objective:To evaluate the clinical efficacy of valsartan for treatment of chronic congestive heart failure.Methods:After basic treatment, sixty patients with chronic congestive heart failure NYHA (Class Ⅲ~Ⅳ) were randomized to combined group and contrast group 1, combined group received varsartan and basic treatment, but contrast group 1, only received basic treatment.And other sixty patients with heart failure who can't bear ACEI were divided into alone group and contrast group 2, alone group received varsartan, contrast group 2 not after stopping ACEI.Results:Alone or combined valsartan significant improved heart function and increased LVEF and reduced left ventricular end-diastolic diameter.Conclusion:Valsartan can be used to treatment of chronic congestive heart failure.
出处 《中国现代医学杂志》 CAS CSCD 2002年第17期68-69,73,共3页 China Journal of Modern Medicine
关键词 缬沙坦 治疗 慢性心力衰竭 疗效 Valsartan Heart Failure
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