小剂量多巴胺联合多巴酚丁胺辅助治疗小儿重症肺炎68例

Low dose dopamine combined with dobutamine in the treatment of 68 cases of severe pneumonia in children

目的:探讨小剂量多巴胺联合多巴酚丁胺辅助治疗小儿重症肺炎的临床效果。方法:收治重症肺炎患儿136例,分为两组,每组各68例。对照组接受常规对症治疗,研究组则在此基础上加用小剂量多巴胺联合多巴酚丁胺辅助治疗。结果:研究组患儿的整体治疗有效率97.06%,高于对照组的86.76%(P<0.05);治疗后,研究组患儿的CRP、NF-KB水平低于对照组(P<0.05)。结论:小剂量多巴胺联合多巴酚丁胺辅助治疗小儿重症肺炎的临床效果确切,消炎、免疫调节作用明显。

Objective:To study the effect of low dose dopamine combined with dobutamine in the treatment of severe pneumonia in children.Methods:136 children with severe pneumonia were selected,they were divided into the two groups.The control group received routine symptomatic treatment,while the study group received low-dose dopamine combined with dobutamine treatment.Results:The overall effective rate of the study group was 97.06%,which was higher than 86.76%of the control group(P<0.05).After treatment,the levels of CRP and NF-KB in the study group were lower than those in the control group(P<0.05).Conclusion:Low dose dopamine combined with dobutamine in adjuvant treatment of children with severe pneumonia has a definite clinical effect,and has obvious anti-inflammatory and immunomodulatory effects.