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风湿病应用糖皮质激素不良反应的观察 被引量:8

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摘要 目的:分析研讨风湿病应用糖皮质激素不良反应。方法:回顾性分析我院2015年3月~2017年12月收治类风湿关节炎患者82例,按照治疗方式分为对照组(常规治疗)和研究组(常规治疗+糖皮质激素治疗),每组41例,观察两组疗效和安全性,并比较。结果:研究组不良反应总发生率34.15%高于对照组的14.63%(P<0.05)。比较两组晨僵持续时间、关节肿胀数、关节压痛数,治疗前P>0.05,治疗后,研究组均低于对照组(P<0.05)。结论:治疗风湿病,在常规抗风湿病药物治疗基础上加以糖皮质激素,可快速控制症状,明显提升疗效,但不良反应多,给药时需注意把握给药剂量和时间,尽量确保用药安全。
作者 王帅
出处 《北方药学》 2019年第2期177-178,共2页 Journal of North Pharmacy
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  • 1乐颖影.低亲和力糖皮质激素受体的研究[J].生理科学进展,1994,25(1):64-66. 被引量:5
  • 2陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:919.
  • 3Arnett F C,Edworthy S M,Bloch D A,et al.The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis[J].Arthritis Rheum,1988,31:315-324.
  • 4Banal F,Dougados M,Combescure C,et al.Sensitivity and specificity of the American College of Rheumatology 1987 criteria for the diagnosis of rheumat -oid arthritis according to disease duration:a systematic literature review and meta-analysis[J].Arthritis Rheum,2009,68:1181-1191.
  • 5Klarenbeek N B,Guler-Yuksel M,Kooij S M,et al.Clinical and radiological outcomes in recent onset rheumatoid arthritis after 5 years of DAS-steered treatment in the best-study[C].ACR/ARHP Annual Scientific Meeting,2008.
  • 6Goekoop R Y P,Vries B J K,Allaart C F,et al.Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the Best study):a randomized,controlled trial[J].Arthritis Rheum,2005,52:3381-3390.
  • 7Knevel R,Schoels M,Huizinga T W,et al.Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs:a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis[J].Ann Rheum Dis,2010,69:987-994.
  • 8Smolen J S,Aletaha D,Bijlsma T W,et al.Treating rheumatoid arthritis to target:recommendations of an international task force[J].Ann Rheum Dis,2010,69:631-637.
  • 9Combe B,Landewe R,Lukas C,et al.EULAR recommendations for the management of early arthritis:report of a task force of the european standing committee for international clinical studies including therapeutics (ESCISIT)[J].Ann Rheum Dis,2007,66:34-45.
  • 10ERIC‐JAN A.KROOT,A. MARGRIETHUISMAN,JENDéVAN ZEBEN,JACQUES M.G.W.WOUTERS,HENK C.VAN PAASSEN.Oral Pulsed Dexamethasone Therapy in Early Rheumatoid Arthritis[J]. Annals of the New York Academy of Sciences . 2006 (1)

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