肝假性淋巴瘤的诊断及治疗

Diagnosis and treatment of hepatic pseudolymphoma

假性淋巴瘤又称反应性淋巴组织增生或结节性淋巴组织样增生,可发生于胃肠道,胰腺,眼眶,皮肤等.而肝脏的假性淋巴瘤极少发生,目前文献多为个案报道,对其发病机制、诊断及治疗预后等多方面缺乏系统性认识.肝假性淋巴瘤的临床表现缺乏特异性,影像学检查及肿瘤标志物常无明显特征.该病确诊主要依赖术后病理与免疫组化染色及基因学检查,及时完整的手术切除是目前首选的治疗方法.

Pseudolymphoma,also known as reactive lymphoid hyperplasia or nodular lymphoid lesion,can occur in the gastrointestinal tract,pancreas,eyelids,skin,etc.;however,pseudolymphoma of the liver rarely occurs.Because of the small number of individual case reports of hepatic pseudolymphoma in most institutions,there is a lack of information available regarding its pathogenesis,optimal treatment,and prognosis.Patients with hepatic pseudolymphoma often present non-specific clinical and imaging features,without specific tumor markers.The diagnosis of this disease mainly depends on postoperative pathological and immunohistochemical evaluations and genetic examination;timely and complete surgical resection is currently the most important treatment.