针药并用治疗下肢深静脉血栓临床观察

Clinical Observations on Combined Use of Acupuncture and Medicine for Lower-limb Deep Venous Thrombosis

目的观察针灸联合现代医学用药治疗下肢深静脉血栓的疗效。方法选取下肢深静脉血栓患者90例,按随机数字表法分为对照组和观察组。对照组给予抗凝、溶栓、扩容治疗;观察组在对照组的基础上给予针灸治疗。观察治疗前后血液动力学指标、D-二聚体浓度、下肢静脉的血流速度。结果对照组患者治疗后,全血黏度、血小板聚集率与治疗前比较差异具有统计学意义(P<0.05);观察组患者治疗后,全血黏度、血浆黏度、红细胞比容、红细胞体积、血小板聚集率与治疗前比较差异均具有统计学意义(P<0.05);治疗后,观察组患者全血黏度、血浆黏度、红细胞比容、红细胞体积、血小板聚集率与对照组比较差异均具有统计学意义(P<0.05)。对照组患者治疗10 d、治疗15 d的D-二聚体浓度低于治疗前,差异具有统计学意义(P<0.05);观察组患者治疗5 d、治疗10 d、治疗15 d的D-二聚体浓度低于治疗前,差异具有统计学意义(P<0.05);观察组治疗5 d、治疗10 d、治疗15 d的D-二聚体浓度均低于同时期对照组,差异均有统计学意义(P<0.05)。两组患者治疗后彩色多普勒显影下肢血流速度比较差异均具有统计学意义(P<0.05);治疗后,观察组患者下肢血流速度高于同时期对照组,差异具有统计学意义(P<0.05)。观察组患者治疗后总有效率明显高于同时期对照组,差异具有统计学意义(P<0.05)。结论针灸联合现代医学用药治疗下肢深静脉血栓疗效明显优于单独用药治疗。

Objective To investigate the efficacy of acupuncture and moxibustion plus modern medication for lower-limb deep venous thrombosis.Method Ninety patients with lower-limb deep venous thrombosis were allocated,using a random number table,to control and observation groups.The control group received anticoagulant,thrombolytic and volume expansion therapy and the observation group,acupuncture and moxibustion in addition.Hemorheological indicators,D-dimer concentration and lower-limb venous blood flow velocity were measured before and after treatment.Result There were statistically significant pre/post-treatment differences in whole blood viscosity and platelet aggregation rate in the control group of patients after treatment(P<0.05).There were statistically significant pre/post-treatment differences in whole blood viscosity,plasma viscosity,hematocrit,erythrocyte electrodeposition rate and platelet aggregation rate in the observation group of patients after treatment(P<0.05).After treatment,there were statistically significant differences in whole blood viscosity,plasma viscosity,hematocrit,erythrocyte electrodeposition rate and platelet aggregation rate between the observation and control groups of patients(P<0.05).D-dimer concentration was lower in the control group of patients at the end of 10 and 20 days of treatment compared with before with astatistically significant difference(P<0.05).D-dimer concentration was lower in the observation group of patients at the end of 5,10 and 20 days of treatment compared with before with a statistically significant difference(P<0.05).At the end of 5,10 and 20 days of treatment,D-dimer concentration was lower in the observation group than in the control group with a statistically significant difference(P<0.05).At the end of treatment,there was a statistically significant pre-/post-treatment difference in color Doppler-visualized lower-limb blood flow velocity in both groups of patients(P<0.05).At the end of treatment,lower-limb blood flow velocity was higher in the observation group of patients than in the control group with a statistically significant difference(P<0.05).After treatment,the total efficacy rate was markedly higher in the observation group of patients than in the control group with a statistically significant difference(P<0.05).Conclusion Acupuncture and moxibustion plus modern medication is significantly more effective than medication alone in treating lower-limb deep venous thrombosis.