口服叶酸辅助治疗高Hcy血症急性心肌梗死的效果研究

Study on the effect of oral folic acid in the treatment of acute myocardial infarction with hyperHcyemia

目的研究分析口服叶酸辅助治疗高Hcy血症急性心肌梗死的临床治疗效果。方法选取本院2014年7月至2016年5月接收的高Hcy血症急性心肌梗死患者86例,均分两组治疗,对照组行临床常规治疗,研究组在该基础上使用口服叶酸进行辅助治疗,对两组的治疗效果进行详细的观察。结果治疗前两组患者的Hcy水平,LVEF、LVESV与LVEDV水平比较,差异无统计学意义;研究组患者治疗后的血Hcy水平明显低于对照组,LVEF水平高于对照组、LVESV与LVEDV水平低于对照组,组间比较差异统计学意义(P<0.05)。结论临床上使用口服叶酸对高Hcy血症急性心肌梗死患者予以辅助治疗,效果更加明显,可有效改善患者的临床症状,值得推广应用。

Objective To study and analyze the clinical efficacy of oral folic acid in the adjuvant treatment of acute myocardial infarction with hyperHcyemia. Methods 86 patients with hyperHcy acute myocardial infarction received in our hospital from July 2014 to May 2016 were divided into two groups. The control group was treated with routine clinical treatment. The study group was treated with oral folic acid as an adjuvant therapy on this basis. The therapeutic effects of the two groups were observed in detail. Results Before treatment, there was no statistical difference in the levels of Hcy, LVEF, LVESV and LVEDV between the two groups. After treatment, the levels of blood Hcy in the study group were significantly lower than those in the control group, the levels of LVEF were higher than those in the control group, and the levels of LVESV and LVEDV were lower than those in the control group. There were significant statistical differences between the two groups (P<0.05). Conclusion Oral folic acid is more effective in the adjuvant treatment of acute myocardial infarction with hyper Hcyemia. It can effectively improve the clinical symptoms of patients, and is worthy of popularization and application.