维持性血液透析患者焦虑抑郁状况及相关因素分析

Anxiety and Depression in Patients with Maintenance Hemodialysis and Related Factors

目的:探究本院维持性血液透析(MHD)患者焦虑和抑郁的发病情况及其与实验室指标的关系。方法:纳入维持性血液透析患者65例,采用医院焦虑抑郁量表(HADS-14)评估其心理状况,并比较不同焦虑、抑郁程度患者的实验室观察指标的差异性。结果:(1)在调查的MHD患者中,焦虑和抑郁障碍的发生率分别为43. 1%(n=28)和80%(n=52);(2)焦虑和抑郁障碍的发生多集中于透析时长50个月以内的血液透析患者;(3)焦虑和抑郁的发生与MHD患者血清血红蛋白水平呈显著负相关(P <0. 01)。结论:焦虑和抑郁障碍在维持性血液透析(MHD)患者中的发病率较高,与患者贫血程度有一定相关性,为临床上对患者进行具有针对性的心理干预治疗提供了一定的理论依据,具体影响机制尚待于今后进一步研究。

Objective: To investigate the incidence of anxiety and depression in patients with maintenance hemodialysis( MHD)in our hospital and its relationship with laboratory parameters. Methods: Sixty-five patients with maintenance hemodialysis were enrolled in this study. The hospital anxiety and depression scale( HADS-14) was used to assess their psychological status. The differences of laboratory observation indexes between patients with different levels of anxiety and depression were compared. Results:( 1) The prevalence rates of anxiety and depression were 43. 1%( n = 28) and 80%( n = 52) in the surveyed patients with MHD.( 2) The incidence of anxiety and depression were mostly in dialysis.( 3) There was a significant negative correlation between the occurrence of anxiety and depression and the serum hemoglobin level in patients with MHD( P < 0. 01). Conclusion: The incidence of anxiety and depression in patients with maintenance hemodialysis( MHD) is high,which is related to the degree of anemia in patients. It provides a theoretical basis for the clinical treatment of patients with targeted psychological intervention The specific impact mechanism is yet to be further studied in the future.