抗病毒药物阻断乙型肝炎母婴传播的研究进展

Research progress of antiviral drugs blocking mother to child transmission of hepatitis B virus

作为当前世界都在着重注意的公共卫生问题,乙型肝炎病毒感染的发生会导致病原传播,危害人体生命安全。在我国,母婴传播是慢性乙型肝炎发生的关键因素,对于受孕的女性,体内如果含有大量的高病毒载量,即使进行了接种处理,仍然有大约14.00%左右的几率会通过母体传播病菌。所以,如何在怀孕阶段合理阻断母婴传播情况,来合理应用抗病毒疗法对乙型肝炎进行治疗,成为目前重点解决的问题。根据大量数据证实,体内高病毒载量的受孕女性在孕周晚期阶段应用抗病毒药物,制订合理的抗病毒方法的计划、药物选择、停药用时等能够合理降低母婴传播几率。针对于此,本文通过综述的形式分析抗病毒药物阻断乙型肝炎母婴传播价值。

As a public health problem that the world is paying attention to,the occurrence of hepatitis B virus infection will lead to the spread of pathogens and endanger human life.In China,mother-to-child transmission is a key factor in the occurrence of chronic hepatitis B.For pregnant women,if there is a large number of high viral load in the body,even if the inoculation treatment,there is still about 14.00%chance of transmission of pathogens through the mother.Therefore,how to block the transmission of mother-to-child in pregnancy,to use antiviral therapy for the treatment of hepatitis B,has become the focus of the problem.According to a large number of data confirmed that high viral load in the body of pregnant women in late gestational weeks,the use of antiviral drugs,the development of a reasonable antiviral method of planning,drug selection,withdrawal time can reasonably reduce the risk of mother-to-child transmission.In view of this,this article through a review of the form of antiviral drugs to block mother-to-child transmission of hepatitis B value.