滴速-滴系数对应关系及对静脉输液速度计算精度的影响

Relationship between dropping rate and droplet coefficient and its influence on calculation accuracy of intravenous infusion speed

目的探讨滴速-滴系数对应关系及对输液速度计算精度的影响。方法在同一温度下[(20±1)℃],测定0.9%氯化钠注射液、5%葡萄糖注射液、10%葡萄糖注射液、葡萄糖氯化钠注射液4种常用溶媒在不同滴速下的滴系数,并对不同溶媒滴系数进行比较。结果不同溶媒的滴系数随着滴速变化趋势类似,即低速输液(0～20 gtt/min)时,滴速-滴系数关系呈非线性关系(以生理盐水为例,曲线拟合函数关系式:Y=22.75-0.27X+0.0069X^2);中高速输液(21～120 gtt/min)时,滴速-滴系数关系呈线性关系(以生理盐水为例,直线拟合函数关系式:Y=20.31-0.022X)。以输液器包装的标称滴系数计算输液速度会导致±10%左右的计算误差。结论滴系数随着滴速的变化趋势并非是线性的,滴速-滴系数对应关系明显影响输液速度的计算精度。

Objective To explore the relationship between dropping rate and droplet coefficient, and its influence on calculation accuracy of intravenous infusion speed.Methods At the same temperature of(20±1)℃, the droplet coefficients of four common so-lvents consisting of 0.9% sodium chloride injection solution, 5% glucose injection solution, 10% glucose injection solution and glucose and sodium chloride injection solution were determined at different dropping velocities, and the drop coefficients using different solvents were compared.Results The variation trend of droplet coefficient along with the dropping rate of different solvents were similar, under the condition of low-speed infusion(0-20 drops/min), the relationship between the dropping rate and droplet coefficient was nonlinear(taking normal saline for example, curve fitting functional formula:Y=22.75-0.27X+0.0069X^2);while in the case of medium and high speed infusion(21-120 drops/min), the relationship was linear(taking normal saline for example, linear fitting functional formula:Y=20.31-0.022X).Infusion speed calculation using the nominal droplet coefficient of the infusion set resulted in a calculation error of around ±10%.Conclusion The variation trend of the droplet coefficient along with the dropping rate is nonlinear, and the corresponding relationship between dropping rate and droplet coefficient obviously influences the calculation accuracy of the infusion rate.