稳定期精神分裂症患者生活质量影响因素分析

Analysis of factors influencing quality of life in patients with stable schizophrenia

目的:调查稳定期精神分裂症患者的生活质量,并分析其影响因素。方法:采用一般情况调查表、生活质量综合评定问卷(GQOLI-74).阳性和阴性综合征量表(PANSS),心理弹性量表(CD-RISC)对5家精神病专科医院门诊就诊的455例稳定期精神分裂症患者进行调查和评估。结果:稳定期精神分裂症患者的生活质量得分为(43.34±7.66)分;CD-RISC得分为(66.19±14.36)分;多元分层回归分析结果显示,婚姻状况、家庭人均月收入、PANSS量表得分、CD-RISC得分是稳定期精神分裂症患者生活质量的影响因素,共解释32.5%的总变异;其中心理弹性可独立解释13.0%的总变异。结论:稳定期精神分裂症患者的生活质量普遍较差,受到婚姻状况、家庭人均月收入、症状严重程度及心理弹性的影响。鉴于心理弹性可以通过培训和干预来提高,临床工作者应开展提高心理弹性的针对性干预,进而提升精神分裂症患者的生活质量。

Objective:To investigate the quality of life in patients with stable schizophrenia and the impact factors.Methods:455 outpatients with stable schizophrenia from 5 psychiatric hospitals were surveyed by the general situation questionnaire,Generic Quality of Life Inventory-74(GQOLI-74),Positive and Negative Symptoms Scale(PANSS),and Connor-Davidson Resilience Scale(CD-RISC).Results:The score of GQOLI-74 was(43.34±7.66);the score of CD-RISC was(66.19±14.36).Multivariate stratified regression showed that marital status,family monthly income,PANSS score,and CD?RISC score were main influencing factors of quality of life in patients with stable schizophrenia,explaining 32.5%of the total variation.CD-RISC score independently explained 13.0%of the total variation.Conclusion:The quality of life in patients with stable schizophrenia is generally poor,which is affected by marital status,family monthly income,severity of symptoms and psychological resilience.The results highlight the importance of improving psychological resilience to promote the quality of life in patients with schizophrenia.