分析骨髓细胞形态检验鉴别难治性贫血与巨幼细胞性贫血的临床价值

Clinical value of bone marrow cell morphology test in differentiating refractory anemia from megaloblastic anemia

目的分析难治性贫血(RA)与巨幼细胞性贫血(MA)经骨髓细胞形态检验鉴别的临床价值。方法选取该院2017年2月至2018年10月收治的贫血患者72例,分为RA组、MA组,各36例,均进行骨髓细胞形态检验,并通过检验情况的对比分析骨髓细胞形态检验鉴别RA与MA的价值。结果与MA组相比,RA组红系病变、粒系病态的占比较高(P<0.05)。RA组PAS阳性率、淋巴样小巨核比率分别为97.2%和94.4%,MA组PAS阳性率、淋巴样小巨核比率分别为0.0%和8.3%,对比存在显著性差异(P<0.05);与MA组相比,RA组RDW较高(P<0.05)。结论骨髓细胞形态检验对RA与MA的鉴别具有较高的临床价值。

Objective To analyze the clinical value of differentiation of refractory anemia ( RA ) and megaloblastic anemia ( MA ) by bone marrow cell morphological examination.Methods 72 patients with anemia admitted to our hospital from February 2017 to October 2018 were selected and divided into RA group and MA group,36 cases in each group.Bone marrow cell morphological examination was conducted,and the value of bone marrow cell morphological examination in differentiating RA from MA was analyzed by comparing the examination results.Results Compared with MA group,RA group had a higher percentage of red lesion and granular lesion ( P <0.05 ).PAS positive rate and lymphoid small megakaryocyte ratio in RA group were 97.2 % and 94.4%,respectively,while PAS positive rate and lymphoid small megakaryocyte ratio in MA group were 0.0% and 8.3%,respectively,with significant difference ( P <0.05).Conclusion Compared with MA group,RDW in RA group is higher ( P <0.05 ).Conclusion:Morphological examination of bone marrow cells is of high clinical value in differentiating RA from MA.