摘要
目的 :探讨 2型糖尿病不同证型骨密度和骨代谢改变的病理生理特征。方法 :测定 93例 2型糖尿病阴虚热盛证、气阴两虚证、阴阳两虚证患者 1~ 4腰椎 (L1 ~L4 )前后位和髋部骨密度 (BMD)以及血清骨钙素 (OC)、抗酒石酸酸性磷酸酶 (TRACP)水平 ,分析各证型上述指标的变化规律。结果 :阴阳两虚证组各腰椎、髋部BMD和OC水平显著低于气阴两虚组、阴虚热盛组和健康人组 ,骨质疏松率高于其它各组 ,而TRACP水平各组无明显差异。结论 :2型糖尿病患者BMD和骨形成减低与肾虚有关 ,印证了中医“肾主骨生髓”
Objective To investigate the pathophysiological characteristics of bone mineral density and bone metabolism in different TCM syndromes of type 2 diabetes mellitus. Methods Bone mineral density (BMD) of lumbar vertebrae 1~4 and the femeur, osteocacin (OC), and tartrate resistant acid phosphatase (TRACP) in 93 patients with type 2 diabetes mellitus with Yin Xu Nei Re Zheng, Qi Yin Liang Xu Zheng and Yin Yang Liang Xu Zheng were studied. Results The BMD of lumbar vertebrae 1~4 and the femeur and the OC levels were higher in the Yin Yang Liang Xu Zheng group than those in the Yin Xu Nei Re Zheng group, Qi Yin Liang Xu Zheng group or healthy persons. The rate of osteoporosis was higher in the Yin Yang Liang Xu Zheng group than those in the other groups. No sighificant difference was found in the TRACP levels in any of the groups. Conclusion The reduction of the BMD and bone formation of type 2 diabetes mellitus patients is related to the dificiency of the kidney. This confirms the theory that 'the kidney is concerned with the bone and produces bone marrow'.
出处
《湖南医科大学学报》
CSCD
北大核心
2002年第5期432-434,共3页
Bulletin of Hunan Medical University
关键词
2型糖尿病
阴虚热盛证
气阴两虚证
阴阳两虚证
骨密度
骨代谢
中医病理学
type 2 diabetes mellitus
Yin Xu Nei Re Zheng
Qi Yin Liang Xu Zheng
Yin Yang Liang Xu Zheng
bone mineral density
bone metabolism