术后经导管(肝)动脉栓塞化疗对合并微血管侵犯的肝癌患者预后影响的研究进展

Advances in efficacy of postoperative transcatheter arterial chemoembolization in hepatocellular carcinoma patients with microvascular invasion

目的肝癌是最常见的原发性恶性肿瘤,手术切除及肝移植均可作为根治性治疗手段,但术后复发率高,严重影响患者预后。而微血管侵犯是肝癌术后复发及转移的独立危险因素。对于术后发现微血管侵犯的肝癌患者,行TACE治疗能否预防肿瘤复发成为一个值得关注的问题。本文就术后辅助性TACE治疗对合并微血管侵犯的肝癌患者预后影响的研究综述,以期为临床肝癌患者术后的进一步治疗提供参考。

Hepatocellular carcinoma is one of the most common malignancies of liver cancer. Partial hepatectomy and liver transplantation are potentially curative treatments in patients with hepatocellular carcinoma. However, the postoperative tumor recurrence rate is high with poor long-term survival outcome. Studies have shown that the presence of microvascular invasion is an independent risk factor of post-resection prognosis. Therefore it draws attention that whether postoperative TACE can prevent the recurrence of liver cancer. This article reviews the research progress postoperative TACE effect on hepatocellular carcinoma patients with microvascular invasion, in order to provide the reference for selection of further treatment.