中西医痤疮病因病机研究撷要

Research on the pathogenesis of acne in traditional Chinese and western medicine

通过梳理中西医对痤疮病因病机的研究,对痤疮的发病机理进行评述,来更全面地认识和提高痤疮的临床疗效,为中西医结合治疗痤疮提供思路。中医认为,痤疮的病因与外感风邪、肺经蕴热;湿热蕴结、痰湿互结;毒热互结,肝肾阴虚;冲任失调有关。西医认为,痤疮发病与机体免疫失衡、痤疮丙酸杆菌作用、炎性因子作用、雄激素作用、毛囊皮脂腺导管角化异常和遗传相关。中医多采用辨证分型方法医治痤疮,疗效显著却缺乏规范的研究方法,难以达成共识;西医治疗痤疮内服类维生素A,外用抗生素联合激素软膏治疗,停药易复发。痤疮治疗应中西医相互结合,方能提高临床疗效。

Through combing the research on the etiology and pathogenesis of acne in traditional Chinese and western medicine,and commenting on the pathogenesis of acne,we can more comprehensively understand and improve the clinical efficacy of acne and provide ideas for the treatment of acne with the combination of traditional Chinese and western medicine.Chinese medicine believes that the etiology of acne is related to the exogenous pathogenic wind and lung meridian heat;accumulation of damp heat and phlegm stasis;toxic heat phlegm and yin deficiency of liver and kidney;disorder of Chong and Ren.Western medicine believes that the main pathogenesis of acne is related to immune imbalance,the role of P.acnes,inflammatory factors,androgen,hair follicle sebaceous duct abnormalities and heredity.Traditional Chinese medicine mostly adopts syndrome differentiation and typing to treat acne,although the curative effect is remarkable,there is no standard research method and it is difficult to reach a consensus;western medicine services often use a class of vitamin A and external antibiotics combined with hormone ointment to treat acne,but it is easy to relapse after drug withdrawal.The author thinks,the treatment of acne should be integrated with traditional Chinese medicine and western medicine,which can better improve the clinical efficacy.