葆宫止血颗粒联合益母草分散片促进产后子宫复旧的临床疗效观察

Clinical observation of Baogongzhixue granules combined with motherwort dispersible tablets on postpartum uterine involution

目的探讨葆宫止血颗粒联合益母草分散片和缩宫素促进子宫复旧的临床疗效。方法选择2016年8月至2017年8月北京中医医院顺义医院妇产科诊治的120例产妇为研究对象,按照不同治疗方法将其分为观察组和对照组,每组60例产妇。观察组产妇采用葆宫止血颗粒联合益母草分散片和缩宫素治疗;对照组产妇采用益母草分散片和缩宫素治疗。比较两组产妇的产后宫底高度、产后24小时出血量、宫缩痛持续时间、恶露持续时间、B超下子宫大小和子宫复旧效果等指标。结果两组产妇一般资料比较,其差异均无统计学意义(P>0.05)。观察组产妇的产后24小时出血量、产后恶露持续时间和宫缩腹痛持续时间均明显少于对照组产妇,其差异均具有统计学意义(均P<0.05)。观察组产妇术后1天宫底高度恢复与对照组产妇相比,其差异无统计学意义(P>0.05);术后第5天、第7天宫底高度低于对照组产妇,其差异均具有统计学意义(均P<0.05);产后7天子宫三径之和比对照组产妇减小,其差异无统计学意义(P>0.05);产后42天子宫三径之和明显比对照组产妇减小,其差异具有统计学意义(P<0.05)。观察组产妇子宫复旧效果优于对照组产妇,其差异具有统计学意义(P<0.05);在安全性指标与不良反应方面,两组产妇差异无统计学意义(P>0.05)。结论葆宫止血颗粒联合益母草分散片和缩宫素能够缩短产妇恶露及腹痛时间,促进子宫收缩,加速产后子宫复旧进程,疗效显著。

Objective To explore the clinical efficacy of Baogongzhixue granules combined with motherwort dispersible tablets on postpartum uterine involution.Methods 120 pregnant women were selected as subjects from the Department of Obstetrics and Gynecology,Shunyi Hospital of Beijing Chinese Medicine Hospital from August 2016 to August 2017.According to different treatment methods,they were divided into observation group and control group,60 women in each group.The observation group was treated with Baogongzhixue granules combined with motherwort dispersible tablets and oxytocin.The control group was treated with motherwort dispersible tablets and oxytocin.The postpartum fundus height,the amount of bleeding within 24 hours postpartum,the duration of uterine contraction pain,the duration of lochia,the size of the uterus under the B-ultrasound and the effect of uterine involution were compared between the two groups.Results There was no statistically significant difference in the general data between the two groups(P>0.05).The 24-hour postpartum hemorrhage,the duration of postpartum lochia and the duration of uterine contractions in the observation group were significantly lower than those in the control group,with statistically significant differences(all P<0.05).There was no significant difference in the recovery of the fundus height between the observation group and the control group(P>0.05).The fundus height on the 5th and 7th day after surgery was lower than that of the control group,with statistically significant difference(all P<0.05).The sum of uterus and three diameters in the observation group was lower than that in the control group,without statistically significant difference on the 7 th day postpartum(P>0.05)but with statistically significant difference on the 42 nd day postpartum(P<0.05).The effect of maternal uterine involution in the observation group was better than that in the control group,with statistically significant difference(P<0.05).There was no statistically significant difference in the safety index and adverse reactions between the two groups(P>0.05).Conclusions Baogongzhixue granules combined with motherwort dispersible tablets can shorten the time of lochia and abdominal pain,promote uterine contractions,and accelerate the process of postpartum uterine involution.