针药联合治疗肝胃郁热型反流性食管炎40例临床观察

40 Cases of Clinical Observation on the Treatment of Liver-Stomach Stagnation-Heat Reflux Esophagitis with Acupuncture and Medicine

目的:观察针药联合治疗肝胃郁热型反流性食管炎的临床效果。方法:选取慢性反流性食管炎患者80例,中医辨证分型均为肝胃郁热型,将其随机分为对照组和治疗组各40例。对照组给予奥美拉唑肠溶胶囊、枸橼酸莫沙必利分散片治疗,治疗组给予针灸联合中药汤剂旋覆代赭汤加减治疗,8周为1个疗程,治疗后对两组进行疗效评价,评价指标包括内镜积分、反流性疾病问卷调查(BDQ)积分及不良反应发生情况。结果:经过治疗,治疗组总有效率为92.5%,优于对照组的82.5%,差异具有统计学意义(P<0.05);两组内镜积分与BDQ积分较治疗前均有所下降,治疗组积分改善优于对照组(P<0.05)。治疗后6个月,治疗组、对照组复发率分别为27.0%和68.6%,差异具有统计学意义(P<0.05)。结论:针药联合治疗肝胃郁热型反流性食管炎临床效率显著,长期效果好,复发率低,不良反应发生率低。

Objective To obderve the clinical effect of acupuncture combined with medicine in the treatment of reflux esophagitis of stagnation heat of liver and stomach.Methods 80 patients with chronic reflux esophagitis were selected.All of them were liver-stomach stagnation-heat type.They were randomly divided into control group and treatment group with 40 cases in each group.The control group was treated with omeprazole enteric-coated capsule and Mosapride Citrate Dispersible Tablet.The treatment group was treated with acupuncture and moxibustion combined with traditional Chinese medicine decoction Xuanfu Daizhe Decoction for 8 weeks.After treatment,the curative effect of the two groups was evaluated.The evaluation indexes included endoscopy score,BDQ score and No.The occurrence of adverse reactions.Results After treatment,the total effective rate of the treatment group was 92.5%,which was better than 82.5%of the control group.The difference was statistically significant(P<0.05).The scores of endoscopy and questionnaire on reflux disease(BDQ)in the two groups were lower than those before treatment,and the scores in the treatment group were better than those in the control group(P<0.05).Six months after treatment,the recurrence rates of the treatment group and the control group were 27.0%and 68.6%,respectively,with statistical significance(P<0.05).Conclusion Acupuncture combined with medicine is effective in the treatment of reflux esophagitis of liver-stomach stagnation-heat type,with good long-term effect,low recurrence rate and low incidence of adverse reactions.