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血清HbA1c对于糖尿病合并冠心病患者住院时间的影响 被引量:3

Effect of Serum HbA1c on Hospitalization Time of Diabetic Patients with Coronary Heart Disease
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摘要 目的分析血清HbA1c对于糖尿病合并冠心病患者的住院时间的影响。方法随机选取天津医科大学总医院于2017年1月-2018年1月收治的糖尿病合并冠心病患者100例,根据HbA1c水平不同分成Ⅰ组(HbA1c≤6.4%)、Ⅱ组(6.41%~7.10%)、Ⅲ组(7.115~8.0%)、Ⅳ组(8.1%及以上),4组患者分别为23例、28例、34例和15例。统计每组患者住院时间和住院费用。检测血清HbA1c水平、心功能,统计并发症。所有患者均接受规范药物治疗方案,包括生活方式管理、病因治疗、消除诱因、药物治疗等。比较四组患者住院时间、住院费用、血清HbA1c水平、心功能、并发症。结果 4组患者住院时间、住院费用差异有统计学意义(P<0.05)。住院时间、住院费用由低到高依次是Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组。4组患者治疗前后血清HbA1c水平差异有统计学意义(P<0.05),经治疗降低;其中4组患者治疗后血清HbA1c水平差异无统计学意义(P>0.05)。治疗前后血清HbA1c水平由低到高依次是Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组。治疗前后4组患者左心室射血分数(LVEF)、左房内径(LA)差异有统计学意义(P<0.05);由低到高依次是Ⅰ组、Ⅱ组、Ⅲ组、Ⅳ组。4组患者并发症发生率差异有统计学意义(P<0.05)。4组患者并发症发生率由高到低依次是Ⅳ组、Ⅲ组、Ⅱ组、Ⅰ组。结论血清HbA1c对于糖尿病合并冠心病患者的住院时间、治疗费用、心功能有影响,会增加患者并发症,建议临床积极控制患者HbA1c水平,采用个性化治疗方案。 Objective To investigate the effect of serum HbA1c on hospitalization time of diabetic patients with coronary heart disease. Methods 100 patients with diabetes mellitus and coronary heart disease in the hospital from January,2017 to January,2018 were selected,and they were randomly divided into four groups according to the level of HbA1c,group I(HbA1c≤6.4%),group II(6.41%≤HbA1c≤7.10%),group III(7.115%≤HbA1 c≤8.0%)and group IV(HbA1 c≥8.1%). All patients received standardized medication. The hospitalization time, hospitalization cost, serum HbA1c level, cardiac function, and complications were compared between the four groups. Results The hospitalization time and hospitalization cost showed significant difference among four groups(P<0.05),which were the lowest in the group I,followed by group II,group III,and group IV. Serum HbA1c levels showed significant difference among four groups before treatment(P<0.05),which were decreased in four groups after treatment,and no statistic difference was found among groups after treatment(P>0.05). Serum HbA1c level was the lowest in the group I,followed by group II,group III,and group IV. LVEF and LA showed significant difference among four groups(P<0.05),which were the lowest in the group I,followed by group II,group III,and group IV. The incidence rate of complications showed significant difference among four groups(P<0.05),which was the lowest in the group I,followed by group II,group III,and group IV. Conclusion Serum HbA1c has an effect on hospitalization time,treatment cost,and cardiac function in patients with diabetes mellitus complicated with coronary heart disease,which will increase the patients’ complication,so the monitor of the HbA1c level is of vital importance for patients.
作者 董萍 DONG Ping(Internal Department,Tanggu Xiangluowan Hospital,Tianjin,300455,China)
出处 《黑龙江医学》 2020年第4期466-469,共4页 Heilongjiang Medical Journal
关键词 HBA1C 糖尿病 冠心病 住院时间 心功能 并发症 HbA1c Diabetes mellitus Coronary heart disease Hospitalization time Cardiac function Complication
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