胰岛素不同给药方法治疗糖尿病的临床效果观察

Observation of Clinical Effect of Different Insulin Administration Methods on Diabetes

目的观察分析胰岛素不同给药方法治疗糖尿病的临床效果。方法随机择取2018年4月—2019年4月于该院收治的122例糖尿病患者作为研究对象,按照入院时间将122例患者分为对照组(n=61例)与观察组(n=61例),分别给予不同的胰岛素治疗方法。对照组行胰岛素常规注射治疗,观察组行胰岛素泵持续注射,比较两组糖尿病的临床有效率、血糖水平、血糖达标时间、胰岛素应用剂量、低血糖发生率。结果观察组61例糖尿病的临床有效率96.7%大于对照组的有效率67.2%,差异有统计学意义(χ^2=7.998,P<0.05)。观察组的低血糖率3.4%小于对照组的14.8%,差异有统计学意义(P<0.05)。观察组治疗后的空腹血糖水平、餐后2 h血糖水平、糖化血红蛋白水平、血糖达标时间、胰岛素应用剂量均小于对照组,差异有统计学意义(P<0.05)。结论应用胰岛素泵持续给药,可有效治疗糖尿病,可更好的控制糖尿病的血糖水平,可减少低血糖率,临床应用安全性更高。

Objective To observe and analyze the clinical effects of different insulin administration methods on diabetes.Methods A total of 122 diabetic patients admitted to the hospital from April 2018 to April 2019 were randomly selected as study subjects.According to the time of admission,122 patients were divided into control group(n=61 cases)and observation group(n=61 patients)were given different insulin treatment methods.The control group received conventional insulin injection treatment,and the observation group received continuous insulin pump injection.The clinical efficacy,blood glucose level,blood glucose reaching time,insulin dosage,and incidence of hypoglycemia were compared between the two groups.Results The clinical effective rate of 61 cases of diabetes in the observation group was 96.7%greater than the effective rate of 67.2%in the control group,and the difference was statistically significant(χ^2=7.998,P<0.05).The hypoglycemia rate in the observation group was 3.4%less than the control group's 14.8%,and the difference was statistically significant(P<0.05).The fasting blood glucose level,2h postprandial blood glucose level,glycated hemoglobin level,blood glucose compliance time,and insulin application dose in the observation group were less than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Continuous application of insulin pump can effectively treat diabetes,better control the blood sugar level of diabetes,reduce the rate of hypoglycemia,and have higher clinical safety.