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晚蚕沙外敷治疗老年人糖尿病周围神经病变的效果评价 被引量:6

Efficacy evaluation of external application of late silkworm sand on diabetic peripheral neuropathy in the elderly
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摘要 目的:评价晚蚕沙外敷治疗寒凝血瘀型糖尿病周围神经病变(DPN)的临床效果。方法:将60例寒凝血瘀型DPN患者随机分为试验组和对照组,每组30例。两组患者均给予甲钴胺基础治疗,试验组在此基础上加用晚蚕沙外敷治疗,疗程均为4周,比较治疗前后两组患者肱踝指数(ABI)和足部震动感觉阈值(VPT)的改善情况。结果:两组患者治疗后左、右侧ABI值均较治疗前上升,治疗后VPT值均较治疗前下降;治疗后试验组左、右侧ABI较对照组上升(t=6.690、8.355,均P=0.000),治疗后试验组较对照组VPT值降低(t=6.447、6.734,均P=0.000)。结果:晚蚕沙外敷治疗寒凝血瘀型DPN能在ABI、VPT方面获益,且具有较好的安全性,值得临床推广。 Objective To evaluate the clinical effects of external application of late silkworm sand on peripheral neuropathy in diabetic(DPN)patients with cold coagulation blood stasis(CCBS).Methods Sixty DPN patients with CCBS were randomly divided into the experimental group and the control group(n=30,each group).Both groups were given routine treatment with mecobalamin,while the experimental group was treated with external application of silkworm sand additionally for 4 weeks.Improvements in brachial-ankle index(ABI)and foot vibration perception threshold(VPT)were compared between the two groups before and after treatment.Results The left and right ABI values were increased and the VPT value was decreased in the two groups after treatment compared with before treatment values.The left and right ABI values were higher(t=6.690 and 8.355,both P=0.000)and the VPT values were lower(t=6.447 and 6.734,both P=0.000)in the experimental group than in the control group after treatment.Conclusions External application of late silkworm sand can improve ABI and VPT with good safety in treating DPN patients with CCBS and should be promoted in clinical practice.
作者 李秀峰 董霞 魏淑凤 Li Xiufeng;Dong Xia;Wei Shufeng(Department of Rheumatology,Fangshan Hospital of Beijing University of Chinese Medicine,Beijing 102400,China)
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2020年第4期399-402,共4页 Chinese Journal of Geriatrics
基金 首都临床特色应用研究与成果推广(Z161100000516023)。
关键词 糖尿病 2型 周围神经系统疾病 Diabetes mellitus type 2 Peripheral nervous system diseases
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