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电离辐射致肠道急性损伤的中医病机探讨 被引量:2

Discussion on TCM pathogenesis of acute intestinal injury caused by ionizing radiation
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摘要 电离辐射所致的肠道急性损伤在临床普遍存在,轻者出现纳差、食欲不振、消化不良;重者出现持续的腹痛腹泻,常伴黏液、脓血,肛门坠痛、里急后重,甚至出现梗阻、糜烂、溃疡、穿孔等症。结合电离辐射的中医病因学特点,电离辐射致肠道急性损伤的中医基本病机为:邪盛伤正,气血乏源,虚实夹杂;升降失常,泌别失职,传导失司;“热”“湿”“毒”“瘀”蕴结,损伤血络;屏障缺失,易于恶化。据证立法,方从法出,有的放矢,这不仅为电离辐射导致的肠道急性损伤寻找有效的中医药防治措施提供了理论依据,也进一步拓展了中医药理论的应用范围,因此具有重要的临床价值和实践意义。 Acute intestinal injury caused by ionizing radiation is prevalent in clinic.Patients of mild cases often show poor appetite,anorexia,dyspepsia,while severe cases show persistent abdominal pain with diarrhea,often accompanied by mucus,pus and blood stool,anus bearing-downpain and tenesmus,even appearing obstruction,erosion,ulcers,perforation and other symptoms.Combining the TCM etiological characteristics of ionizing radiation,the basic TCM pathogenesis of acute intestinal injury caused by ionizing radiation can be summarized as following,the strong pathogenic qi hurting the vital qi,qi and blood loses its origin,intermingled deficiency and excess;disharmony between ascending and descending,dysfunction of separating clear and excreting turbid,and transmission disorder.The blood collaterals were damaged by accumulation of heat,damp,toxin and blood stasis,and the loss of intestinal barriers leads to deterioration easily.Then we can get the principle and prescription of the treatment based on TCM syndrome differentiation.It not only provides a theoretical basis for finding effective prevention and treatment measures of acute intestinal injury caused by ionizing radiation,but also further expands the application scope of TCM theory,so it has important clinical value and practical significance.
作者 李盼飞 卢曦 何昶昊 王艳 王安 胡素敏 LI Panfei;LU Xi;HE Changhao;WANG Yan;WANG An;HU Sumin(School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China)
出处 《环球中医药》 CAS 2020年第4期616-619,共4页 Global Traditional Chinese Medicine
基金 国家自然科学基金(11475035,11675027) 北京中医药大学新奥奖励基金(2016XAJLJJ-001)。
关键词 电离辐射 肠道损伤 腹泻 中医病机 脾胃 肠道屏障 Ionizing radiation Intestinal damage Diarrhea TCM pathogenesis Spleen and stomach Intestinal barrier
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