芍药汤加减结合针刺治疗溃疡性结肠炎湿热蕴结证活动期临床效果分析

Analysis of Clinical Effect of Shaoyao Decoction Combined with Acupuncture on Ulcerative Colitis Damp-heat Accumulation Syndrome in Active Phase

目的分析芍药汤加减结合针刺治疗溃疡性结肠炎湿热蕴结证活动期临床效果。方法将于2018年1月—2019年1月该院收治的溃疡性结肠炎患者共有100例,将其作为观察对象,随机分为观察组50例,对照组50例,对观察组给予芍药汤加减结合针刺治疗,对照组患者实施针刺治疗,对比观察两组患者治疗前后体征评分(腹痛、里急后重、便脓血、腹泻、肛门灼热)以及治疗效果和结肠镜病理改变评分变化。结果两组患者治疗前体征评分比较差异无统计学意义[(2.92±0.34)分、(2.98±0.54)分、(2.24±0.32)分、(2.54±0.79)分、(2.07±0.45)分、(2.91±0.32)分、(2.97±0.56)分、(2.23±0.36)分、(2.58±0.78)分、(2.06±0.46)分],治疗后观察组患者体征评分(0.51±0.43)分、(0.41±0.28)分、(0.49±0.42)分、(0.71±0.23)分、(0.62±0.12)分显著优于对照组(1.51±0.79)分、(1.62±0.48)分、(1.45±0.84)分、(1.32±0.86)分、(1.45±0.32)分(t=7.861、15.397、7.228、4.845、17.173,P=0.000、0.000、0.000、0.000、0.000),观察组患者治疗有效率100%明显高于对照组患者治疗有效率84%(χ^2=8.696,P=0.003),两组患者治疗前结肠镜病理评分(4.98±1.54)分、(5.02±1.24)分、(4.96±1.52)分、(5.04±1.23)分,差异无统计学意义(t=0.065、0.081,P=0.948、0.936),治疗后观察组患者结肠镜病理评分(1.12±0.83)分、(1.24±0.75)分,明显低于对照组患者结肠镜病理评分(3.24±1.11)分、(3.23±1.08)分(t=10.816、10.702,P=0.000、0.000)。结论应用芍药汤加减结合针刺治疗溃疡性结肠炎,有效保护患者的结肠粘膜,改善患者的临床症状,安全性高,临床效果显著。

Objective To analyze the clinical effect of Shaoyao Decoction combined with acupuncture in the treatment of ulcerative colitis damp-heat syndrome.Methods A total of 100 patients with ulcerative colitis will be treated in the hospital from January 2018 to January 2019.They will be randomly divided into observation group 50 cases,control group 50,and Shaoyao decoction combined with acupuncture treatment,the control group was treated with acupuncture,and the scores of abdominal signs,abdominal pain,post-emergency,postpartum hemorrhage,diarrhea,and anal burning were compared before and after treatment.Results There was no statistically significant difference between the two groups of patients before treatment[(2.92±0.34)points,(2.98±0.54)points,(2.24±0.32)points,(2.54±0.79)points,(2.07±0.45)points,(2.91±0.32)points,(2.97±0.56)points,(2.23±0.36)points,(2.58±0.78)points,(2.06±0.46)points],the scores of the physical signs of the observation group after treatment(0.51±0.43)points,(0.41±0.28)points,(0.49±0.42)points,(0.71±0.23)points,(0.62±0.12)points were significantly better than those of the control group(1.51±0.79)points,(1.62±0.48)points,(1.45±0.84)points,(1.32±0.86)points,(1.45±0.32)points(t=7.861,15.397,7.228,4.845,17.173,P=0.000,0.000,0.000,0.000,0.000).The treatment efficiency of the observation group was significantly higher than that of the control group by 100%.The effective rate of treatment was 84%(χ^2=8.696,P=0.003).There was no statistically significant difference in the colonoscopy pathological scores(4.98±1.54)points,(5.02±1.24)points,(4.96±1.52)points,(5.04±1.23)points between the two groups of patients(t=0.065,0.081,P=0.948,0.936),the colonoscopy pathological scores of patients in the observation group(1.12±0.83)points,(1.24±0.75)points after treatment were significantly lower than those of the control group(3.24±1.11)points,(3.23±1.08)points,(t=10.816,10.702,P=0.000,0.000).Conclusion The application of Shaoyao Decoction combined with acupuncture in the treatment of ulcerative colitis can effectively protect the colonic mucosa of patients,improve the clinical symptoms of patients,and has high safety and significant clinical effects.