定向软通道颅内血肿引流术联合自体血清治疗高血压脑出血的效果

Effect of directional soft-channel intracranial hematoma drainage combined with autologous serum in the treatment of hypertensive cerebral hemorrhage

目的定向软通道颅内血肿引流术联合自体血清治疗高血压脑出血的效果。方法选取2018年1月~2019年6月我院收治的70例高血压脑出血患者作为研究对象,按照随机数字表法将其分为对照组(35例)和观察组(35例),对照组患者采用定向软通道颅内血肿引流术联合尿激酶治疗,观察组患者采用定向软通道颅内血肿引流术联合自体血清治疗。比较两组患者的临床治疗总有效率、并发症总发生率及格拉斯哥昏迷量表(GCS)和斯堪的纳维亚卒中量表(SSS)评分变化。结果观察组患者的临床治疗总有效率为97.14%,高于对照组的82.86%,差异有统计学意义(P<0.05);观察组患者的并发症总发生率为5.71%,低于对照组的22.86%,差异有统计学意义(P<0.05);治疗前,两组患者的GCS、SSS评分比较,差异无统计学意义(P>0.05);治疗后,两组患者的GCS评分高于治疗前,SSS评分低于治疗前,且观察组患者的GCS评分高于对照组,SSS评分低于对照组,差异有统计学意义(P<0.05)。结论高血压脑出血患者采用定向软通道颅内血肿引流术联合自体血清治疗的效果明显,可显著改善患者的GCS及SSS评分,改善其昏迷和神经功能损伤程度,治疗总有效率高,并发症少。

Objective To investigate the effect of directional soft-channel intracranial hematoma drainage combined with autologous serum in the treatment of hypertensive cerebral hemorrhage.Methods From January 2018 to June 2019,70 patients with hypertensive cerebral hemorrhage treated in our hospital were selected as the research subjects.They were divided into control group(n=35)and observation group(n=35)according to the random number table method.In the control group,directional soft-channel intracranial hematoma drainage combined with Urokinase was used,and in the observation group,directional soft-channel intracranial hematoma drainage combined with autologous serum was applied.The total clinical treatment efficiency,total incidence of complications,and changes in the Glasgow coma scale(GCS)and Scandinavian stroke scale(SSS)scores of patients in the two groups were compared.Results The total effective rate of clinical treatment in the observation group was 97.14%,higher than 82.86%in the control group,and the difference was statistically significant(P<0.05).The total incidence of complications in the observation group was 5.71%,lower than 22.86%in the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant difference in GCS or SSS scores between the two groups(P>0.05).After treatment,the GCS scores in the two groups were higher than those before treatment,the SSS scores were lower than those before treatment,in the observation group,the GCS score was higher than that of the control group,the SSS score was lower than that of the control group,and the differences were statistically significant(P<0.05).Conclusion Patients with hypertensive intracerebral hemorrhage treated with directional soft-channel intracranial hematoma drainage combined with autologous serum obtains remarkable effects,which can greatly improve the GCS and SSS scores of patients,and improve their coma and neurological injury with a high total effective rate and few complications.