右美托咪定、异丙酚复合麻醉针对脑肿瘤切除手术患者的脑保护效果对比分析

Comparative Analysis of Combined Anesthesia with Dexmetiomide and Propofol in the Treatment of Patients Undergoing Brain Tumor Resection

目的对脑肿瘤切除手术患者分别应用右美托咪定、异丙酚麻醉维持,并对比其脑保护效果。方法选取脑肿瘤切除手术患者80例,将患者分为两组。观察组患者40例,使用右美托咪定麻醉维持;对照组患者40例,使用异丙酚麻醉维持,对比两组患者的脑氧代谢、脑损伤相关蛋白等指标。结果术后24 h,观察组患者的SjvO2、OER、NSE、S100β等指标均明显低于对照组(P<0.05)。结论右美托咪定麻醉对患者的脑保护效应更佳,具有较高的应用价值。

Objective To compare the effects of dexmedetomidine and propofol combined anesthesia needles on brain protection in patients undergoing brain tumor resection.Methods 80 patients with brain tumors were selected and divided into two groups.40 patients in the observation group were given dexmedetomidine combined anesthesia;40 patients in the control group were given propofol combined anesthesia needle.The indexes of cerebral oxygen metabolism and brain injury related proteins were compared between the two groups.Results 24 hours after operation,the SjvO2,OER,NSE and S100 beta in the observation group were significantly lower than those in the control group(P<0.05).Conclusions Dextrometridine accords with anesthesia and has better brain protection effect for patients,and has higher application value.