阿卡波糖联合二甲双胍治疗2型糖尿病的疗效

Efficacy of Acarbose Combined With Metformin in the Treatment of Type 2 Diabetes

目的探究阿卡波糖联合二甲双胍治疗老年2型糖尿病的疗效。方法选取本院2018年3月—2018年12月收治的120例老年2型糖尿病患者,采用摸球法分为联合组和参与组,各60例。2组患者均接受二甲双胍治疗,联合组另辅以阿卡波糖治疗。治疗后观察疗效,包括治疗总有效率及治疗后空腹血糖、餐后2 h血糖、糖化血红蛋白。结果联合组治疗总有效率96.67%,高于参与组的80.00%(P<0.05)。联合组空腹血糖、餐后2 h血糖、糖化血红蛋白均低于参与组(P<0.05)。结论阿卡波糖联合二甲双胍治疗老年2型糖尿病的疗效显著,可有效控制患者血糖,提高安全性及可行性。

Objectiv To investigate the efficacy of acarbose combined with metformin in the treatment of type 2 diabetes in the elderly.Methods From March 20 to December 2018,120 elderly patients with type 2 diabetes mellitus admitted to our hospital were enrolled in the joint group and the participating group,60 cases each.Both groups received metformin treatment,and the combination group was supplemented with acarbose.The curative effect was observed after treatment,including the total effective rate of treatment and fasting blood glucose after treatment,2 h postprandial blood glucose,and glycated hemoglobin.Results The total effective rate was 96.67%in the combined group and 80.00%in the participating group.The difference was statistically significant(P<0.05).Fasting blood glucose,postprandial 2h blood glucose,and glycosylated hemoglobin in the combined group were lower than those in the participating group,and the correlation was statistically significant(P<0.05).Conclusion Acarbose combined with metformin is effective in the treatment of type 2 diabetes in the elderly.It can effectively control the blood sugar of patients,improve safety and feasibility.