腹膜透析患者磷清除影响因素的研究进展

Research progress in the influencing factors for phosphorus clearance in peritoneal dialysis patients

高磷血症是慢性肾脏病患者的常见并发症,是腹膜透析患者心血管疾病及全因死亡率的重要预测因素,严重影响腹膜透析患者的生活质量及预后。腹膜透析患者高磷血症很普遍,临床中血磷管理非常复杂,涉及到饮食、磷结合剂、残肾功能、腹膜透析多个方面。但是关于腹膜透析患者磷清除影响因素仍存在争议。本文对腹膜透析患者磷清除影响因素研究作一综述,希望对腹膜透析患者磷清除影响因素有更清晰的认识,从而找到干预的切入点。

Hyperphosphatemia is a common complication of chronic kidney diseases and is also important predictors of cardiovascular disease and all-cause mortality in peritoneal dialysis(PD) patients. Hyperphosphatemia is common in PD patients and seriously affects their quality of life and prognosis. Clinically, the complicated management of serum phosphorus involves diet, phosphorus binding agents, residual kidney function and PD. However, the factors affecting phosphorus clearance in PD patients are still controversial. This article reviews the research progress about the influencing factors on phosphorus clearance in PD patients, hoping to make a better comprehension of this issue and to find key points for intervention.