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急性肾损伤患者长期预后及肾功能恢复研究进展 被引量:6

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摘要 急性肾损伤(acute kidney injury,AKI)是急性肾功能丢失的一种综合征,是危重症患者常见并发症之一[1]。AKI的全球发病率日益增长,不仅增加患者的短期病死率,同时导致慢性肾功能不全、心血管不良事件及远期死亡的发生风险增加[2]。随着对AKI的不断深入探索,人们不再局限于改善AKI患者的短期预后,越来越多研究开始探索影响AKI患者长期预后的危险因素。近期AKI患者住院期间的肾功能恢复模式被提出,并且发现与患者长期预后相关[3-4]。因此,提高AKI患者的长期预后可以通过改变近期的肾功能恢复情况来实现。而近年来,一些生物标志物对预测近期肾功能恢复有一定价值[5-7],为临床改善AKI患者的长期预后提供了新思路。本文主要对AKI患者的长期预后、影响预后的危险因素、肾功能恢复模式及相关生物标志物进行阐述。
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2020年第9期1143-1147,共5页 Chinese Journal of Emergency Medicine
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