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散结镇痛胶囊化学成分、药理作用及临床应用研究进展 被引量:11

Research Progress on Chemical Constituents,Pharmacological Action and Clinical Application of Sanjie Zhentong Capsule
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摘要 散结镇痛胶囊由龙血竭、三七、浙贝母、薏苡仁4味常用中药组成,具有软坚散结,化瘀定痛的功效,现代研究表明散结镇痛胶囊中含有黄酮类、生物碱类、皂苷类以及酚酸类等多种化学成分;临床上主要用于治疗痛经、月经不调、不孕、子宫内膜异位等症,疗效确切,已成为治疗妇科疾病的首选中成药。因此,本文通过查阅近年来国内外文献,对散结镇痛胶囊的化学成分、药理作用及临床应用进行综述,以期为其进一步研究和二次开发利用提供参考。 Sanjie Zhentong Capsule(SJZTC)consist of four common used traditional Chinese medicine,includingResina Draconis(Longxuejie),Panax notoginseng(Burk.)F.H.Chen(Sanqi),Fritillaria thunbergii Miq.(Zhebeimu),Coix lacryma-jobi L.var.mayuen(Roman.)Stapf(Yiyiren).It has the effect of Ruanjiansanjie and Huayudingtong.Modern studies indicate that the chemical composition of SJZTC mainly includes flavonoids,alkaloids,saponins,phenolic acids and so on.SJZTC has been widely used for the treatment of dysmenorrhea,irregular menstruation,aspermy and endometriosis,has a good therapeutic effect in clinical practice,and is the first line drug among traditional Chinese medicine in the treatment of gynecological diseases.This paper reviewed and summarized the domestic and foreign researches of SJZTC in recent years about the chemical constituents,pharmacological action and clinical application,which provided a reference and support for further study and secondary development of the formula.
作者 葛雯 陶倩 阮洪生 陈宏降 Ge Wen;Tao Qian;Ruan Hongsheng;Chen Hongjiang(Zhejiang Pharmaceutical College,Ningbo 315100)
出处 《中药药理与临床》 CAS CSCD 北大核心 2020年第4期227-232,共6页 Pharmacology and Clinics of Chinese Materia Medica
基金 浙江省公益技术研究计划资助(编号:LGF18H280005) 浙江省教育厅项目(编号:Y201840577)。
关键词 散结镇痛胶囊 化学成分 药理研究 临床应用 Sanjie Zhentong Capsule chemical constituents pharmacological action clinical application
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