右美托咪定联合盐酸纳美芬在小儿喉罩麻醉中的应用效果

Application effect of Dexmedetomidine combined with Namefen Hydrochloride on laryngeal mask anesthesia in children

目的探讨右美托咪定联合盐酸纳美芬在小儿喉罩麻醉中的应用效果。方法选取东莞台心医院2017年4月~2019年6月进行喉罩麻醉手术的患儿70例,使用随机数字表法分为研究组和对照组,各35例。两组患儿均使用丙泊酚、舒芬太尼、七氟烷等常规药物,对照组使用右美托咪定麻醉,研究组使用右美托咪定联合盐酸纳美芬麻醉。观察两组的呼吸频率和心率情况、恢复情况和不良反应发生情况。结果麻醉后研究组的呼吸频率、心率高于对照组,差异有统计学意义(P<0.05);研究组的清醒时间、自主呼吸恢复时间、喉罩拔出时间均短于对照组,差异有统计学意义(P<0.05);研究组的不良反应总发生率(2.86%)低于对照组(17.14%),差异有统计学意义(P<0.05)。结论右美托咪定联合盐酸纳美芬在小儿喉罩麻醉中的应用效果显著,不良反应较低。

Objective To investigate the application effect of Dexmedetomidine combined with Nmefene Hydrochloride on laryngeal mask anesthesia in children.Methods A total of 70 children who underwent pediatric laryngeal mask anesthesia in Dongguan Taixin Hospital from April 2017 to June 2019 were selected,they were divided into the study group and the control group according to the random number table method,each group had 35 cases.Children in both groups were treated with routine anesthetic drugs such as Propofol,Sufentanil and Sevoflurane,the control group used Dexmedetomidine,the study group used Dexmedetomidine combined with Namefen Hydrochloride.The breathing of the children after anesthesia,recovery and adverse reactions were observed.Results After anesthesia,the respiratory rate and heart rate of the study group were higher than those of the control group,with statistically significant differences(P<0.05);the waking time,spontaneous breathing recovery time and laryngeal mask extraction time of the study group were shorter than those of the control group,with statistically significant differences(P<0.05);the overall incidence of adverse reactions in the study group(2.86%)was lower than that in the control group(17.14%),and the difference was statistically significant(P<0.05).Conclusion Dexmedetomidine combined with Namefen Hydrochloride has a significant effect on laryngeal mask anesthesia in children,with low adverse reactions.