甘精胰岛素联合二甲双胍治疗糖尿病肥胖症的效果

Effect of the Treatment of Insulin Glargine Combined With Metformin on Diabetes Obesity

目的对比分析初发2型糖尿病伴肥胖症治疗中甘精胰岛素+二甲双胍的应用效果。方法随机选取本院2016年3月—2018年11月期间收治200例初发2型糖尿病伴肥胖症患者设为研究对象,开展回顾性研究分析。依据患者治疗用药的不同将其分为对照组、试验组,组内样本容量均为100例。对比甘精胰岛素、二甲双胍临床治疗效果及影响。结果治疗前,两组血糖生化指标、体脂率指标组间对比差异无统计学意义(P>0.05);试验组治疗后的血糖生化指标、体脂率指标、血糖复常时间及胰岛素用量均明显优于对照组(P<0.05)。结论甘精胰岛素、二甲双胍治疗初发2型糖尿病伴肥胖症效果显著。

Objective To compare and analyze the effects of insulin glargine+metformin in the treatment of type 2 diabetes mellitus with obesity.Methods 200 patients with type 2 diabetes mellitus with obesity were selected and divided into control group and experimental group.Blood glucose biochemical indicators,body fat percentage index,blood glucose recurrence time and insulin dosage were compared before and after treatment.Results Before treatment,there was no significant difference between the two groups in blood glucose biochemical index and body fat percentage index(P>0.05).The blood glucose biochemical index,body fat percentage index,blood glucose relapse time and insulin dosage in the experimental group were significantly better than the control group(P<0.05).Conclusion Insulin glargine and metformin are effective in the treatment of type 2 diabetes mellitus with obesity.