负压封闭结合局部氧疗对创伤性慢性伤口愈合的影响

Effect of vacuum sealing combined with local oxygen therapy on traumatic chronic wounds

目的探究负压封闭结合局部氧疗对创伤性慢性伤口愈合的影响。方法选取2017年6月至2019年6月暨南大学附属第一医院收治的82例创伤性慢性伤口患者,采用随机数字表法分为对照组和观察组,每组41例。对照组采用负压封闭治疗,观察组采用负压封闭结合局部氧疗的方式治疗,比较治疗3、6、9、12d时两组的肉芽组织覆盖率、愈合计分,以及两组的治愈率、愈合时间及细菌阳性率情况。结果治疗6、9、12d时观察组的肉芽组织覆盖率高于对照组,差异有显著性(P<0.05);治疗12d时观察组的愈合计分低于对照组,差异有显著性(P<0.05)。观察组的治愈率(87.8%)高于对照组(63.4%),愈合时间[(39.53±9.27)d]短于对照组[(52.96±9.57)d],细菌阳性率(17.1%)低于对照组(48.8%),差异均有显著性(P<0.05)。结论对创伤性慢性伤口采用负压封闭结合局部氧疗的方式进行治疗,可促进创面肉芽组织生长,降低创面细菌阳性率,缩短创面愈合时间,提高临床治愈率。

Objective To explore the effect of negative pressure sealing combined with local oxygen therapy on the healing of traumatic chronic wounds.Method A total of 82 patients with traumatic chronic wounds admitted to the First Affiliated Hospital of Jinan University from June 2017 to June 2019 were divided into control group and observation group by random number table method,with 41 cases in each group.The control group was treated with negative pressure sealing,and the observation group was treated with negative pressure sealing combined with local oxygen therapy.The granulation tissue coverage,healing scores,and the cure rate of the two groups were compared on the 3,6,9,12 days of treatment.Result The granulation tissue coverage rate of the observation group was higher than that of the control group on the 6,9,and 12 days of treatment,and the healing score of the observation group was lower than that of the control group on the 12th day of treatment.The difference was significant(P<0.05).The cure rate(87.8%)of the observation group was higher than that of the control group(63.4%),the healing time[(39.53±9.27)d]was shorter than that of the control group[(52.96±9.57)d],and the positive rate of bacteria(17.1%)was lower In the control group(48.8%),the difference was significant(P<0.05).Conclusion In patients with traumatic chronic wounds,negative pressure sealing combined with local oxygen therapy can promote the growth of wound granulation tissue,reduce the positive rate of wound bacteria,shorten the wound healing time,and improve the clinical cure rate.