基于肠道菌群探讨从脾胃论治男性不育症

Discussion on the treatment of male infertility from spleen and stomach based on intestinal flora

人类繁衍生息以男女两性的生理结构为基础,而且受到各种生理病理因素的影响和制约,是生理基础的自然选择结果。不孕不育越来越受到人们的关注,据报道在其中男性不育约占半数,男性不育症越来越成为影响人类生殖和健康不可忽略的严重问题之一。人体内正常的肠道微生物群是维持人体新陈代谢的重要物质,与人体的生理病理密切相关。本文基于肠道菌群、中医脾胃理论、男性不育症三者之间的相关性,从肠道菌群角度出发,通过中医健运脾胃的方药调节肠道菌群失调的作用,从而为男性不育症的临床研究及治疗提供更多思路,并为中医药在防治该疾病的作用机制上提供理论依据。

Human reproduction is based on the physiological structures of men and women and affected and restricted by various physiological factors.Infertility is now receiving more and more attention and male infertility reportedly accounts for about half of the infertility cases and is becoming one of the serious problems affecting human reproduction and health.The normal intestinal microbiota flora is an important substance to maintain normal metabolism of the human body and closely related to its physiology and pathology.This paper discusses the correlation between the intestinal flora,spleen and stomach theory in TCM and male infertility,from the perspective of the gut flora and the TCM prescriptions for strengthening the spleen and stomach and regulating the imbalance of intestinal flora,aiming to provide some more ideas and theoretical evidence for the clinical studies and treatment of male infertility.