无创通气治疗晚期发生呼吸衰竭的弥漫性间质性肺病疗效分析

Analysis of the Curative Effect of Non-invasive Ventilation in the Treatment of Diffuse Interstitial Lung Disease with Late Respiratory Failure

目的探讨无创通气治疗晚期发生呼吸衰竭的弥漫性间质性肺病疗效。方法选择2018年4月—2019年4月在该院进行治疗的晚期发生呼吸衰竭的弥漫性间质性肺病患者64例,将患者随机分为普通组和实验组,每组32例。普通组患者行有创通气治疗,实验组患者行无创通气治疗,比较分析两组患者的恢复情况、临床指标及并发症发生率。结果两组患者的呼吸频率、心率、PaCO2、PaO2水平数据差异无统计学意义(t=1.509、0.688、0.335、0.556,P>0.05)。实验组患者的住院时间、通气时间明显短于普通组,住院费用明显低于普通组,差异有统计学意义(t=24.479、3.292、2.650,P<0.05)。实验组患者的并发症发生率为3.13%(1例);普通组患者的并发症发生率为25.00%(8例),实验组并发症发生率显著低于普通组,差异有统计学意义(χ^(2)=4.010,P<0.05)。结论对晚期发生呼吸衰竭的弥漫性间质性肺病患者进行无创通气治疗,可缩短住院时间、通气时间,减少患者的经济压力,有效降低并发症的发生率,呈现出更显著的治疗效果。

Objective To explore the efficacy of non-invasive ventilation in the treatment of diffuse interstitial lung disease with late respiratory failure.Methods Sixty-four patients with diffuse interstitial lung disease who developed respiratory failure in the hospital were selected for treatment in the hospital.The specific selection time was from April 2018 to April 2019.The patients were randomly divided into general and experimental groups.There were 32 cases in each group.Patients in the general group were treated with invasive ventilation,and patients in the experimental group were treated with non-invasive ventilation.The recovery,clinical indicators,and complication rates of the two groups were compared and analyzed.Results There were no statistically significant differences in the respiratory rate,heart rate,PaCO2 and PaO2 levels of the two groups of patients(t=1.509,0.688,0.335,0.556,P>0.05).The hospitalization time and ventilation time of the experimental group were significantly shorter than those of the general group,and the hospitalization expenses were significantly lower than those of the general group.The difference was statistically significant(t=24.479,3.292,2.650,P<0.05).The complication rate of the experimental group was 3.13%(1 case);the complication rate of the general group was 25.00%(8 cases).The complication rate of the experimental group was significantly lower than that of the general group,and the difference was statistically significant(χ^(2)=4.010,P<0.05).Conclusion Non-invasive ventilation treatment for patients with diffuse interstitial lung disease who have advanced respiratory failure can shorten hospital stay and ventilation time,reduce the economic pressure of patients,effectively reduce the incidence of complications,and present a more significant therapeutic effect.