调Q-Nd:YAG激光与液氮冷冻治疗面部脂溢性角化病的疗效比较

Efficacy of Q-switched Nd:YAG laser and liquid nitrogen cryotherapy in the treatment of facial seborrheic keratosis

目的探讨调Q-Nd:YAG激光和液氮冷冻治疗面部脂溢性角化病的临床疗效。方法选取2020年5月-2020年12我院门诊确诊的面部脂溢性角化病患者121例,分为激光组和冷冻组。激光组采用调Q-Nd:YAG激光治疗,冷冻组采用液氮冷冻治疗,治疗一个月后评估疗效。结果激光组有效率为98.69%,冷冻组有效率为79.65%,两组间有显著统计学差异(P<0.01);治疗后,两组患者出现色素沉着率分别为6.53%和29.65%,两组间有显著统计学差异(P<0.01)。结论调Q-Nd:YAG激光治疗脂溢性角化病较液氮冷冻治疗更加安全、有效,值得临床推广应用。

Objective To investigate the clinical efficacy of Q-switched Nd:YAG laser and liquid nitrogen cryotherapy in the treatment of facial seborrheic keratosis.Methods A total of 121 patients with facial seborrheic keratosis diagnosed in outpatient department of our hospital from May 2020 to December 2020 were selected and divided into laser group and cryotherapy group.Q-switched Nd:YAG laser was used in the laser group,and liquid nitrogen cryotherapy was used in the cryotherapy group.The efficacy was evaluated after one month of treatment.Results The effective rate of laser group was 98.69%,and that of cryotherapy group was 79.65%,with significant statistical difference between the two groups(P<0.01).After treatment,the pigmentation rate in 2 groups was 6.53%and 29.65%,respectively,and there was a statistically significant difference between 2 groups(P<0.01).Conclusion Q-switched Nd:YAG laser in the treatment of seborrheic keratosis is safer and more effective than liquid nitrogen cryotherapy,which is worthy of clinical application.