摘要
乳腺癌是女性常见的恶性肿瘤之一。由于近年来乳腺癌诊疗手段的丰富和靶向治疗药物的广泛应用,乳腺癌患者的生存期较前有所延长,死亡率呈现下降的趋势。然而,与靶向药物治疗相关的心血管毒性在乳腺癌患者治疗过程中的发生率也随之升高,本文就乳腺癌靶向药物治疗相关心血管毒性的研究进展作一综述。
Breast cancer is one of the most common malignant tumors in women.Because of the abundance of diagnosis and treatment methods and the wide application of targeted therapy drugs in recent years,the survival time of breast cancer patients is longer than before and the mortality rate shows a downward trend.However,the incidence of cardiovascular toxicity associated with targeted drug therapy in breast cancer patients is also increasing.This article reviews the research progress of cardiovascular toxicity associated with targeted drug therapy in breast cancer.
作者
王岩
孟文静
佟仲生
WANG Yan;MENG Wenjing;TONG Zhongsheng(Department of Breast Medical Oncology,Tianjin Medical University Cancer Institute and Hospital/National Clinical Research Center for Cancer/Key Laboratory of Breast Cancer Prevention and Therapy,Ministry of Education/Tianjin’s Clinical Research Center for Cancer/Key Laboratory of Cancer Prevention and Therapy,Tianjin 300060,China)
出处
《肿瘤防治研究》
CAS
CSCD
2021年第5期524-529,共6页
Cancer Research on Prevention and Treatment
基金
天津市卫生行业重点攻关项目(16KG128)
天津市自然科学基金(18JCYBJC91600)。
关键词
乳腺癌
靶向治疗
心血管毒性
Breast cancer
Targeted therapy
Cardiovascular toxicity