一种用于微血管功能无创评估的系统设计和应用

Design and Application of a Non-Invasive Assessment System for Microvascular Function

目的为解决微循环功能障碍威胁人类健康却难以诊断的问题,本文设计了一个有效的微血管无创评估系统。方法系统由STM32主控板、加热片、TMP117高精度温度传感器、上位机通信模块组成,加热片对人体手指皮肤进行热刺激,传感器采集热刺激前后的温度信号,并传送给上位机的时频分析软件进行分析,提取出内皮调节、神经调节和肌源调节等子频段的信号,进一步评估人体的微血管调节功能。结果使用该系统对受试者进行试验,健康人员的评估分数在60分及以上,微血管功能风险的人员的评估分数在60分以下,健康状态越好,得分越高。结论该系统使用方便,成本低廉,对于疾病的早期筛查和评估具有重要的意义。

Objective To solve the problem that microcirculatory dysfunction threatened human health but was difficult to diagnose,an effective non-invasive assessment system of microvascular was designed.Methods The system was constituted by STM32 control board,heating plates,TMP117 high precision temperature sensor and PC communication module.The heating plate was used to heat the skin of finger.The temperature sensor collected the temperature signals before and after thermal stimulation,and transmitted them to the time-frequency analysis software on the PC.Then,the signals of endothelial,neural,myogenic regulation were extracted to further evaluate the microvascular function of human body.Results The subjects were tested using the system,the assessment scores of healthy individuals were above 60,and those at risk of microvascular function were below 60.The better the health condition,the higher the score.Conclusion The system is easy to use and low cost,which is of great significance for early screening and evaluation of diseases.