卵巢储备功能下降病因及治疗的中西医研究进展

Research Progress of Etiology of Decreased Ovarian Reserve and Treatment of Traditional Chinese Medicine and Western Medicine

近年来卵巢储备功能下降(DOR)的发病率呈逐年增高且年轻化的趋势,目前已成为中西医研究的热点。西医学认为DOR由遗传性、免疫性、医源性等多种因素引起;中医认为DOR分为虚证和实证,且以虚证为主,尤以肾虚为根本原因,临床常脾肾两虚、心肾不交并见,实证主要由气滞血瘀导致,且临床常虚实夹杂。西医以激素补充治疗、诱导排卵、辅助生殖治疗等措施为主,中医则以中药、针灸、耳穴压豆等治疗为主。而中西医结合治疗DOR可更好地保护女性的生殖健康。

In recent years,decreased ovarian reserve(DOR)has a higher morbidity and younger onset trend,which has become a research hotspot of both traditional Chinese medicine(TCM)and western medicine currently.In western medicine,it′s considered that genetic,immunologic and iatrogenic factors are the main causes of DOR.According to the theory of TCM,DOR is due to deficiency syndrome and excess syndrome,of which deficiency is the main cause and kidney deficiency is the root cause.The common clinical syndrome is spleen and kidney deficiency and disharmony of heart and kidney,while the excessive DOR is due to qi stagnation and blood stasis,and deficient and excessive syndrome are often mixed clinically.Western medicine adopts hormone supplementing therapy,induced ovulation and assisted reproductive technology as the major treatment of DOR.Herb,acupuncture,ear acupoint bean pressing,etc.are the primary therapies of TCM.Combined treatment of TCM and western medicine of DOR can better protect the female reproductive health.