女性尖锐湿疣患者治疗后性功能障碍情况及危险因素分析

Analysis of Sexual Dysfunction and Risk Factors in Female Patients with Condyloma Acuminatum after Treatment

【目的】探讨女性尖锐湿疣患者治疗后性功能障碍情况及危险因素。【方法】回顾性分析2018年1月至2020年1月在陕西省康复医院诊治的96例女性尖锐湿疣患者的临床资料。分析患者治疗后性功能障碍发生情况,并统计患者年龄、教育程度、不良生活习惯等一般资料,采用单因素和多因素Logistic回归分析患者治疗后发生性功能障碍的影响因素。【结果】96例患者均成功完成治疗,有33例发生治疗后性功能障碍,占34.38%,纳入性功能障碍组;63例未发生治疗后性功能障碍,占65.62%,纳入无性功能障碍组。单因素分析结果显示:女性尖锐湿疣患者治疗后性功能障碍与教育程度、合并疾病、人乳头瘤病毒16型(HPV16).饮酒、熬夜、皮损部位具有相关性(P<0.05)。多因素Logistic回归分析显示:教育程度(OR=1.147,95%CI=1.021〜1.289)、HPV16(OR=2.517,95%CI=1.185〜5.346)、饮酒(OK=4.156,95%CI=1.325〜13.036)、熬夜(OR=4.153,95%CI=1.354〜12.738)、皮损部位(OR=5.913,95%CI=2.385-14.660)是女性尖锐湿疣患者治疗后性功能障碍的独立危险因素(P<0.05)。【结论】女性尖锐湿疣患者治疗后性功能出现障碍与患者教育程度、HPV16、饮酒、熬夜、皮损部位密切相关。

【Objective】To investigate the sexual dysfunction and risk factors of female patients with condyloma acuminatum after treatment.【Objective】The clinical data of 96 female patients with condyloma acuminatum treated in Shaanxi rehabilitation hospital from January 2018 to January 2020 were analyzed retrospectively.The incidence of sexual dysfunction after treatment was analyzed,and the general data such as age,education and bad living habits were counted.The influencing factors of sexual dysfunction after treatment were analyzed by univariate and multivariate logistic regression.【Results】A total of 96 patients completed the treatment sue-cessfully,and 33 patients had sexual dysfunction after treatment,accounting for 34.38%;63 cases had no sexual dysfunction after treatment,accounting for 65.62%,which were included in the asexual dysfunction group.Univariate analysis showed that the sexual dysfunction of female patients with condyloma acuminatum after treatment was correlated with education,combined diseases,human papillomavirus 16(HPV16),drinking,staying up late and the location of skin lesions(P<0.05).Multivariate logistic regression analysis showed that education level(OR=1.147,95%CI=1.021〜1.289),HPV16(OR=2.517,95%CI=1.185〜5.346),drinking(OR=4.156,95%CI=1.325〜13.036),staying up late(OR=4.153,95%CI=1.354〜12.738),skin lesion site(OR=5.913,95%CT=2.385〜14.660)was an independent risk factor for sexual dysfunction in female patients with condyloma acuminatum after treatment(P<0.05).【Conclusion】The disorder of sexual function in female patients with condyloma acuminatum after treatment is closely related to their education,HPV16,drinking,staying up late and the location of skin lesions.