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2015-2019年国家自然科学基金资助的动脉粥样硬化项目情况及研究热点分析 被引量:4

Analysis of the situation and research hotspots of atherosclerosis projects funded by the National Natural Science Foundation of China from 2015 to 2019
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摘要 目的对2015—2019年国家自然基金资助的动脉硬化相关项目进行分析,探讨当前该领域的研究热点,为后续开展动脉粥样硬化相关研究提供参考。方法统计2015—2019年立项的动脉粥样硬化相关项目,对立项年度、类型、学科分布等情况进行分析,并应用CiteSpace软件进行关键词可视化分析,探究当前国家自然科学基金对于动脉粥样硬化领域的资助热点。结果近5年动脉粥样硬化相关项目的立项总数为662项,每年立项数目整体较为稳定。其中所属医学科学部有612项(92.4%)占比最高,立项呈现多学科协同现象。资助项目地区分布不均衡,立项集中于北京、上海、广东等地区。关键词共现结果显示,巨噬细胞、炎症、内皮细胞为出现频率前3名的关键词。关键词聚类结果显示内皮细胞、巨噬细胞、微RNA为前3名的研究类团。结论国家自然科学基金是国家对于基础研究的重要支撑,研究者应把握研究热点,多学科协同,多技术联用,推动动脉粥样硬化研究的更深层次探索。 Objective To analyze the arteriosclerosis-related projects funded by the National Natural Science Foundation of China from 2015 to 2019,to discuss current research hotspots in this field,and to provide references for subsequent research on atherosclerosis.Methods The atherosclerosis-related projects approved from 2015 to 2019 were counted,and the project year,type,and subject distribution were analyzed,while CiteSpace software for keyword visualization analysis was applied to explore the current funding hotspots of the National Natural Science Foundation of China in the field of atherosclerosis.Results In the past five years,the total number of atherosclerosis-related projects has been 662 items,and the number of projects each year has been relatively stable.Among them,the medical science department has 612 items(92.4%),which account for the highest proportion,and the establishment of the project showed the phenomenon of multi-disciplinary collaboration.The regional distribution of funded projects was uneven,and the projects were concentrated in Beijing,Shanghai,Guangdong and other regions.Keyword co-occurrence results showed that macrophages,inflammation,and endothelial cells were the top three keywords with frequency.Keyword clustering results showed that endothelial cells,macrophages,and microRNA were the top three research clusters.Conclusion The National Natural Science Foundation of China is an important national support for basic research.Researchers should grasp research hotspots,multi-disciplinary collaboration,and multi-technology joint application to promote deeper exploration of atherosclerosis research.
作者 张芸楠 张翼 王依繁 韩嘉伦 林佰弟 闫佳琳 石秀锦 林阳 ZHANG Yunnan;ZHANG Yi;WANG Yifan;HAN Jialun;LIN Baidi;YAN Jialin;SHI Xiujin;LIN Yang(Department of Pharmacy,Beijing Anzhen Hospital,Capital Medical University,Beijing100029,China;School of Pharmaceutical Sciences,Capital Medical University,Beijing100069,China)
出处 《中国医药导报》 CAS 2021年第27期7-11,16,共6页 China Medical Herald
基金 科技部十三五“新药创制”重大专项(2017ZX09304017) 北京市医院管理局“扬帆计划”(ZYLX201805)。
关键词 国家自然科学基金 动脉粥样硬化 研究热点 可视化分析 National Natural Science Foundation of China Atherosclerosis Research hotspots Visualization analysis
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